Human Growth Hormone Abuse in Male Weightlifters

被引：43

作者：

Brennan, Brian P. ^{[1
,2
]}

Kanayama, Gen ^{[1
,2
]}

Hudson, James I. ^{[1
,2
]}

Pope, Harrison G., Jr. ^{[1
,2
]}

机构：

[1] McLean Hosp, Biol Psychiat Lab, Belmont, MA 02478 USA

[2] Harvard Univ, Sch Med, Dept Psychiat, Boston, MA 02115 USA

来源：

AMERICAN JOURNAL ON ADDICTIONS | 2011年 / 20卷 / 01期

关键词：

ANDROGENIC STEROID USE; CARDIOVASCULAR-SYSTEM; I AXIS; USERS; ADOLESCENTS; DEPENDENCE; MORTALITY; NONUSERS; HEALTH; ISSUES;

D O I：

10.1111/j.1521-0391.2010.00093.x

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

In a study of performance-enhancing substance use among 231 experienced young male weightlifters, we found that 27 (12%) reported illicit use of human growth hormone (HGH) or its bioactive derivative, insulin-like growth factor-1. All of these 27 men also reported use of anabolic-androgenic steroids (AAS) and 22 (81%) met criteria for current or past AAS dependence. Fifteen (56%) also reported current or past dependence on opioids, cocaine, and/or ecstasy. These findings suggest that among young male weightlifters, illicit HGH use has become a common form of substance abuse, frequently associated with both AAS dependence and classical substance dependence. (Am J Addict 2010;00:1-5).

引用

页码：9 / 13

页数：5

共 40 条

[1]

[Anonymous], 1998, STRUCTURED CLIN INTE

[2]

[Anonymous], ANABOLICS

[3] Does acromegaly enhance mortality? [J].

Ayuk, John ;

Sheppard, Michael C. .

REVIEWS IN ENDOCRINE & METABOLIC DISORDERS, 2008, 9 (01) :33-39

[4] Long-Term Anabolic-Androgenic Steroid Use Is Associated With Left Ventricular Dysfunction [J].

Baggish, Aaron L. ;

Weiner, Rory B. ;

Kanayama, Gen ;

Hudson, James I. ;

Picard, Michael H. ;

Hutter, Adolph M., Jr. ;

Pope, Harrison G., Jr. .

CIRCULATION-HEART FAILURE, 2010, 3 (04) :472-U15

[5] Steroid and prescription medicine abuse in the health and fitness community: A regional study [J].

Baker, J. S. ;

Graham, M. R. ;

Davies, B. .

EUROPEAN JOURNAL OF INTERNAL MEDICINE, 2006, 17 (07) :479-484

[6] Supraphysiological doses of GH induce rapid changes in cardiac morphology and function [J].

Cittadini, A ;

Berggren, A ;

Longobardi, S ;

Ehrnborg, C ;

Napoli, R ;

Rosén, T ;

Fazio, S ;

Caidahl, K ;

Bengtsson, BÅ ;

Saccà, L .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2002, 87 (04) :1654-1659

[7] The heart: an end-organ of GH action [J].

Colao, A ;

Vitale, G ;

Pivonello, R ;

Ciccarelli, A ;

Di Somma, C ;

Lombardi, G .

EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2004, 151 :S93-S101

[8] The GH-IGF-I axis and the cardiovascular system: clinical implications [J].

Colao, Annamaria .

CLINICAL ENDOCRINOLOGY, 2008, 69 (03) :347-358

[9]

DAHLBERG T, 2008, ASS PRESS 1029

[10]

*EC21, EC21 GLOB B2B MARK

← 1 2 3 4 →