Statement: Cancer treatments and ovarian reserve

被引：3
作者：
Basille, C. [1 ,2 ]
Torre, A. [1 ,2 ]
Grynberg, M. [1 ,2 ]
Gallot, V. [1 ,2 ]
Frydman, R. [1 ,2 ,3 ]
Fanchin, R. [1 ,2 ,3 ]
机构：
[1] Univ Paris 11, F-92140 Clamart, France
[2] Hop Antoine Beclere, AP HP, Serv Gynecol Obstet & Med Reprod, F-92141 Clamart, France
[3] INSERM, U782, F-92140 Clamart, France
来源：
JOURNAL DE GYNECOLOGIE OBSTETRIQUE ET BIOLOGIE DE LA REPRODUCTION | 2010年 / 39卷 / 06期
关键词：
Fertility; Chemotherapy; Radiotherapy; Ovarian reserve; ANTI-MULLERIAN HORMONE; GERM-CELL TUMORS; LONG-TERM SURVIVORS; ASSISTED REPRODUCTIVE TECHNOLOGY; BONE-MARROW-TRANSPLANTATION; FERTILITY-SPARING SURGERY; IN-VITRO FERTILIZATION; BREAST-CANCER; ADJUVANT CHEMOTHERAPY; HODGKINS-DISEASE;
D O I：
10.1016/j.jgyn.2010.05.012
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Purpose of review. -The purpose of this review is to update the reader on the impact of cancer treatment on fertility, the options of fertility preservation, and the new markers to assess ovarian function. Essential points. -The impact of chemotherapy and radiotherapy on fertility depends on the drugs and the doses used. It often affects ovarian reserve significantly, and the presence of menstruation is not a reliable reflection of it. Fertility preservation techniques, such as ovarian protection, and preferably cryopreservation combined with assisted reproductive medicine, should be individually discussed and possibly proposed to the patients. The use of new markers for ovarian reserve assessment will help to evaluate infraclinic chemotherapy and/or radiotherapy-induced effects on ovarian reserve, prior to clinical effects. (C) 2010 Elsevier Masson SAS. All rights reserved
引用
收藏
页码：433 / 443
页数：11
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