Medical Applications of Tissue-Equivalent, Organic-Based Flexible Direct X-Ray Detectors

被引：28

作者：

Basirico, Laura ^{[1
,2
]}

Ciavatti, Andrea ^{[1
,2
]}

Fratelli, Ilaria ^{[1
,2
]}

Dreossi, Diego ^{[3
]}

Tromba, Giuliana ^{[3
]}

Lai, Stefano ^{[4
]}

Cosseddu, Piero ^{[4
]}

Bonfiglio, Annalisa ^{[4
]}

Mariotti, Francesco ^{[5
]}

Dalla Val, Carlo ^{[5
]}

Bellucci, Valerio ^{[6
]}

Anthony, John E. ^{[7
]}

Fraboni, Beatrice ^{[1
,2
]}

机构：

[1] Univ Bologna, Dept Phys & Astron, Bologna, Italy

[2] Natl Inst Nucl Phys INFN, Sect Bologna, Bologna, Italy

[3] Elettra Sincrotrone Trieste, Trieste, Italy

[4] Univ Cagliari, Dept Elect & Elect Engn, Cagliari, Italy

[5] Skan X Radiol Devices SpA Bologna, Bologna, Italy

[6] Skanray Europe Srl, Bologna, Italy

[7] Univ Kentucky, Ctr Appl Energy Res, 3572 Iron Works Pike, Lexington, KY 40511 USA

来源：

FRONTIERS IN PHYSICS | 2020年 / 8卷

基金：

美国国家科学基金会;

关键词：

organic X-ray detectors; wearable electronics; flexible electronics; thin films; medical dosimetry; SEMICONDUCTING SINGLE-CRYSTALS; RADIATION DETECTORS; LOW-COST; THIN; PHOTODETECTORS; SCINTILLATOR; PHOTODIODES; SENSORS; FILMS;

D O I：

10.3389/fphy.2020.00013

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

The aim of this study is to assess direct X-ray detectors based on organic thin films, fabricated onto flexible plastic substrates, and operating at ultra-low bias (<1 V), for different medical applications. With this purpose, flexible fully organic pixelated X-ray detectors have been tested at the imaging beamline SYRMEP (SYnchrotron Radiation for MEdical Physics) at the Italian synchrotron Elettra, Trieste. The detectors' performance has been assessed for potential employment both as reliable wearable personal dosimeters for patients and as flexible X-ray medical imaging systems. A spatial resolution of 1.4 lp mm(-1) with a contrast of 0.37 has been evaluated. Finally, we validate the detector using X-ray doses and energies typically employed for actual medical radiography, and using X-ray beam pulses provided by a commercial dental radiography system, recording a sensitivity of 1.6 x 10(5) mu C Gy(-1) cm(-3) with a linear response with increasing of the dose rates and a reliable signal to 100 ms X-rays pulses.

引用

页数：11

共 46 条

[41] Proving Scalability of an Organic Semiconductor To Print a TFT-Active Matrix Using a Roll-to-Roll Gravure [J].

Sun, Junfeng ;

Park, Hyejin ;

Jung, Younsu ;

Rajbhandari, Grishmi ;

Maskey, Bijendra Bishow ;

Sapkota, Ashish ;

Azuma, Yasuo ;

Majima, Yutaka ;

Cho, Gyoujin .

ACS OMEGA, 2017, 2 (09) :5766-5774

[42] Response of organic photodiode fabricated directly on plastic scintillator to X-rays [J].

Takada, Eiji ;

Fujii, Kazuo ;

Imai, Hideyuki ;

Okada, Hiroyuki ;

Namito, Yoshihito ;

Nakamura, Takashi .

JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY, 2015, 52 (01) :104-108

[43] Fully Spray Coated Organic Photodiodes [J].

Tedde, Sandro F. ;

Kern, Johannes ;

Sterzl, Tobias ;

Fuerst, Jens ;

Lugli, Paolo ;

Hayden, Oliver .

NANO LETTERS, 2009, 9 (03) :980-983

[44] High sensitivity organic inorganic hybrid X-ray detectors with direct transduction and broadband response [J].

Thirimanne, H. M. ;

Jayawardena, K. D. G. I. ;

Parnell, A. J. ;

Bandara, R. M. I. ;

Karalasingam, A. ;

Pani, S. ;

Huerdler, J. E. ;

Lidzey, D. G. ;

Tedde, S. F. ;

Nisbet, A. ;

Mills, C. A. ;

Silva, S. R. P. .

NATURE COMMUNICATIONS, 2018, 9

[45] The SYRMEP Beamline of Elettra: Clinical Mammography and Bio-medical Applications [J].

Tromba, G. ;

Longo, R. ;

Abrami, A. ;

Arfelli, F. ;

Astolfo, A. ;

Bregant, P. ;

Brun, F. ;

Casarin, K. ;

Chenda, V. ;

Dreossi, D. ;

Hola, M. ;

Kaiser, J. ;

Mancini, L. ;

Menk, R. H. ;

Quai, E. ;

Quaia, E. ;

Rigon, L. ;

Rokvic, T. ;

Sodini, N. ;

Sanabor, D. ;

Schultke, E. ;

Tonutti, M. ;

Vascotto, A. ;

Zanconati, F. ;

Cova, M. ;

Castelli, E. .

6TH INTERNATIONAL CONFERENCE ON MEDICAL APPLICATIONS OF SYNCHROTRON RADIATION, 2010, 1266 :18-+

[46]

Yakunin S, 2015, NAT PHOTONICS, V9, P444, DOI [10.1038/nphoton.2015.82, 10.1038/NPHOTON.2015.82]

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