Isotope effects on binding

被引：13

作者：

Rakowski, K ^{[1
]}

Paneth, P ^{[1
]}

机构：

[1] TECH UNIV LODZ,DEPT CHEM,PL-90924 LODZ,POLAND

来源：

JOURNAL OF MOLECULAR STRUCTURE | 1996年 / 378卷 / 01期

关键词：

isotope effect; binding of ligand to enzyme; enzymic process;

D O I：

10.1016/0022-2860(95)09146-7

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Several recent reports on isotope effects in processes of binding ligands (inhibitors, coenzymes, and reactants) to enzymes challenge the dogma that such processes do not exhibit a measurable isotopic fractionation. The origin and consequences of studying enzymic reaction mechanisms of binding isotope effects are discussed herein.

引用

页码：35 / 43

页数：9

共 41 条

[1] ELUCIDATION OF MODE OF BINDING OF OXYGEN TO IRON IN OXYHEMOGLOBIN BY INFRARED SPECTROSCOPY [J].