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Cystic fibrosis papers of the year 2017
被引:2
|作者:
Doull, Iolo
[1
,2
]
机构:
[1] Childrens Hosp Wales, Dept Paediat Resp Med, Cardiff CF14 4XN, S Glam, Wales
[2] Childrens Hosp Wales, Paediat Cyst Fibrosis Ctr, Cardiff CF14 4XN, S Glam, Wales
关键词:
Cystic fibrosis;
Ivacaftor;
Lumacaftor;
Tezacaftor;
Doxycycline;
MRSA;
RESISTANT STAPHYLOCOCCUS-AUREUS;
PHE508DEL CFTR MUTATION;
AGED;
6-11;
YEARS;
TEZACAFTOR-IVACAFTOR;
LUNG-FUNCTION;
LUMACAFTOR/IVACAFTOR;
EFFICACY;
F508DEL-CFTR;
COMBINATION;
PHASE-3;
D O I:
10.1016/j.prrv.2018.03.001
中图分类号:
R72 [儿科学];
学科分类号:
100202 ;
摘要:
The number of published articles on Cystic Fibrosis (CF) continues to increase year on year. The evidence base for small molecule therapies in CF has continued to expand, with evidence for lumacaftor/ivacaftor in younger patients and longer-term evidence in adults, and pivotal studies on tezacaftor/ivacaftor. There were reports on emerging CFTR mutation agnostic therapies, and new evidence for long standing therapies. (C) 2018 Elsevier Ltd. All rights reserved.
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页码:2 / 5
页数:4
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