ETS-related gene ERG expression in AML patients is significantly associated with NPM1 mutation status

被引：4

作者：

Hamalainen, Mauri ^{[1
]}

Juvonen, Vesa ^{[2
]}

Haikio, Satu ^{[3
]}

Lakkala, Taina ^{[3
]}

Johansson, Janita ^{[4
]}

Pelliniemi, Tarja-Terttu ^{[1
]}

Salmi, Toivo T. ^{[5
]}

Remes, Kari ^{[6
]}

Kairisto, Veli ^{[2
]}

机构：

[1] Univ Turku, Dept Clin Chem, TYKS, FI-20520 Turku, Finland

[2] Turku Univ, Cent Hosp, Mol Genet Lab, TYKSLAB, Turku, Finland

[3] Univ Turku, Dept Biochem & Med Genet, FI-20520 Turku, Finland

[4] Turku Univ, Cent Hosp, Hematol Lab, TYKSLAB, Turku, Finland

[5] Turku Univ, Cent Hosp, Dept Pediat, Turku, Finland

[6] Turku Univ, Cent Hosp, Dept Med, Turku, Finland

来源：

EUROPEAN JOURNAL OF HAEMATOLOGY | 2010年 / 85卷 / 04期

关键词：

ACUTE MYELOID-LEUKEMIA; OVEREXPRESSION;

D O I：

10.1111/j.1600-0609.2010.01483.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：361 / 362

页数：2

共 9 条

[1] Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21:: Amplification discloses overexpression of APP, ETS2, and ERG genes [J].

Baldus, CD ;

Liyanarachchi, S ;

Mrózek, K ;

Auer, H ;

Tanner, SM ;

Guimond, M ;

Ruppert, AS ;

Mohamed, N ;

Davuluri, RV ;

Caligiuri, MA ;

Bloomfield, CD ;

de la Chapelle, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (11) :3915-3920

[2] Wilms tumour gene 1 overexpression in bone marrow as a marker for minimal residual disease in acute myeloid leukaemia [J].

Haemaelaeinen, Mauri M. ;

Kairisto, Veli ;

Juvonen, Vesa ;

Johansson, Janita ;

Auren, Jukka ;

Kohonen, Kati ;

Remes, Kari ;

Salmi, Toivo T. ;

Helenius, Hans ;

Pelliniemi, Tarja-Terttu .

EUROPEAN JOURNAL OF HAEMATOLOGY, 2008, 80 (03) :201-207

[3]

Langebrake C, 2006, HAEMATOLOGICA, V91, P1473

[4] The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells [J].

Loughran, Stephen J. ;

Kruse, Elizabeth A. ;

Hacking, Douglas F. ;

de Graaf, Carolyn A. ;

Hyland, Craig D. ;

Willson, Tracy A. ;

Henley, Katya J. ;

Ellis, Sarah ;

Voss, Anne K. ;

Metcalf, Donald ;

Hilton, Douglas J. ;

Alexander, Warren S. ;

Kile, Benjamin T. .

NATURE IMMUNOLOGY, 2008, 9 (07) :810-819

[5] Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype:: A cancer and leukemia group B study [J].

Marcucci, G ;

Baldus, CD ;

Ruppert, AS ;

Radmacher, MD ;

Mrózek, K ;

Whitman, SP ;

Kolitz, JE ;

Edwards, CG ;

Vardiman, JW ;

Powell, BL ;

Baer, MR ;

Moore, JO ;

Perrotti, D ;

Caligiuri, MA ;

Carroll, AJ ;

Larson, RA ;

de la Chapelle, A ;

Bloomfield, CD .

JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (36) :9234-9242

[6]

Marcucci G, 2007, J CLIN ONCOL, V25, P3337, DOI 10.1200/JCO.2007.10.8720

[7] ERG Expression Is an Independent Prognostic Factor and Allows Refined Risk Stratification in Cytogenetically Normal Acute Myeloid Leukemia: A Comprehensive Analysis of ERG, MN1, and BAALC Transcript Levels Using Oligonucleotide Microarrays [J].

Metzeler, Klaus H. ;

Dufour, Annika ;

Benthaus, Tobias ;

Hummel, Manuela ;

Sauerland, Maria-Cristina ;

Heinecke, Achim ;

Berdel, Wolfgang E. ;

Buechner, Thomas ;

Woermann, Bernhard ;

Mansmann, Ulrich ;

Braess, Jan ;

Spiekermann, Karsten ;

Hiddemann, Wolfgang ;

Buske, Christian ;

Bohlander, Stefan K. .

JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (30) :5031-5038

[8] BAALC is an important predictor of refractoriness to chemotherapy and poor survival in intermediate-risk acute myeloid leukemia (AML) [J].

Santamaria, Carlos ;

Chillon, Maria C. ;

Garcia-Sanz, Ramon ;

Perez, Cristina ;

Caballero, Maria D. ;

Mateos, Maria V. ;

Ramos, Fernando ;

Garcia de Coca, Alfonso ;

Alonso, Jose M. ;

Giraldo, Pilar ;

Bernal, Teresa ;

Queizan, Jose A. ;

Rodriguez, Juan N. ;

Puig, Noemi ;

Balanzategui, Ana ;

Sarasquete, Maria E. ;

Alcoceba, Miguel ;

Diaz-Mediavilla, Joaquin ;

San Miguel, Jesus ;

Gonzalez, Marcos .

ANNALS OF HEMATOLOGY, 2010, 89 (05) :453-458

[9] Molecular stratification model for prognosis in cytogenetically normal acute myeloid leukemia [J].

Santamaria, Carlos M. ;

Chillon, Maria C. ;

Garcia-Sanz, Ramon ;

Perez, Cristina ;

Caballero, Maria D. ;

Ramos, Fernando ;

Garcia de Coca, Alfonso ;

Alonso, Jose M. ;

Giraldo, Pilar ;

Bernal, Teresa ;

Queizan, Jose A. ;

Rodriguez, Juan N. ;

Fernandez-Abellan, Pascual ;

Barez, Abelardo ;

Penarrubia, Maria J. ;

Balanzategui, Ana ;

Vidriales, Maria B. ;

Sarasquete, Maria E. ;

Alcoceba, Miguel ;

Diaz-Mediavilla, Joaquin ;

San Miguel, Jesus F. ;

Gonzalez, Marcos .

BLOOD, 2009, 114 (01) :148-152

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