APPLICATIONS OF MULTICOMPONENT ASSEMBLY PROCESSES TO THE FACILE SYNTHESES OF DIVERSELY FUNCTIONALIZED NITROGEN HETEROCYCLES

被引：11
作者：
Donald, James R. [1 ]
Granger, Brett A.
Hardy, Simon
Sahn, James J.
Martin, Stephen F.
机构：
[1] Univ Texas Austin, Dept Chem & Biochem, Austin, TX 78712 USA
来源：
HETEROCYCLES | 2012年 / 84卷 / 02期
基金：
美国国家卫生研究院;
关键词：
Diversity Oriented Synthesis; Imine and Iminium Ions; Cyclization; Cross Coupling Reaction; Privileged Structure; PRIVILEGED STRUCTURES; DERIVATIVES; REAGENTS; CONDENSATION; ANTAGONISTS; ALKYLATION; ALKALOIDS; ARYLATION; ANALOGS; POTENT;
D O I：
10.3987/COM-11-5(P)92
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Several multicomponent assembly processes have been developed for the synthesis of intermediates that may be elaborated by a variety of cyclizations to generate a diverse array of highly functionalized heterocycles from readily-available starting materials. The overall approach enables the efficient preparation of libraries of small molecules derived from fused, privileged scaffolds.
引用
收藏
页码：1089 / 1112
页数：24
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