Short report:: Clostridium difficile in adult patients with nosocomial diarrhea in a Costa Rican hospital

被引：17

作者：

Zumbado-Salas, Roberto ^{[1
]}

Gamboa-Coronado, Maria del Mar ^{[1
]}

Rodriguez-Cavallini, Evelyn ^{[1
]}

Chaves-Olarte, Esteban ^{[1
]}

机构：

[1] Univ Costa Rica, Fac Microbiol, Ctr Invest Enfermedades Trop, Lab Invest Bacteriol Anaerobia, San Jose 2060, Costa Rica

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2008年 / 79卷 / 02期

关键词：

D O I：

10.4269/ajtmh.2008.79.164

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Stool samples from 104 adult patients with nosocomial antibiotic-associated diarrhea were analyzed for Clostridium difficile by cultivation, toxin A inmunoenzymatic detection, and toxin B cytotoxic detection. The isolates were additionally screened for the toxin genes by polymerase chain reaction. C difficile was isolated from 26 samples, and the toxins ware directly detected in another 5 samples. Toxin A and B genes were detected in all toxigenic bacterial isolates. The detection rate of 30% indicates that C difficile is a major etiologic agent of nosocomial diarrhea in Costa Rica.

引用

页码：164 / 165

页数：2

共 19 条

[1] Survey of incidence of Clostridium difficile infection in Canadian hospitals and diagnostic approaches [J].