Sentinel lymph node evaluation in squamous cell carcinoma of the head and neck

被引：114
作者：
Stoeckli, SJ
Steinert, H
Pfaltz, M
Schmid, S
机构：
[1] Univ Zurich Hosp, Clin Otorhinolaryngol Head & Neck Surg, Div Nucl Med, CH-8091 Zurich, Switzerland
[2] Univ Zurich Hosp, Dept Pathol, CH-8091 Zurich, Switzerland
来源：
OTOLARYNGOLOGY-HEAD AND NECK SURGERY | 2001年 / 125卷 / 03期
关键词：
D O I：
10.1067/mhn.2001.118074
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
OBJECTIVE. The aim of our study was to assess the feasibility of sentinel lymph node (SLN) radiolocalization in No neck in squamous cell head and neck carcinoma and its predictive value for occult metastasis. Study Design: Nineteen patients of an open prospective trial. SETTING: After peritumoral injection of a 99m Tc labeled radiocolloid, the SLN was localized preoperatively by lymphoscintigraphy and intraoperatively through the intact skin by a hand-held gamma-probe. The histology of the SLN and the nodes of the elective neck dissection were compared. RESULTS: Localization of the SLN by lymphoscintigraphy was possible in 18 of 19, and with the handheld gamma-probe in all 19 patients. Six SLN revealed occult metastatic disease. No skip metastasis were found in the 13 neck specimen with negative SLN. CONCLUSION. SLN evaluation in No neck in squamous cell carcinoma of the head and neck is accurately feasible and seems to adequately predict the presence of occult metastasis.
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页码：221 / 226
页数：6
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