Neurologic Manifestations of Primary Sjogren Syndrome

被引：69

作者：

Margaretten, Mary ^{[1
]}

机构：

[1] Univ Calif San Francisco, Div Rheumatol, 1001 Potrero St,Bldg 30, San Francisco, CA 94110 USA

来源：

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 2017年 / 43卷 / 04期

关键词：

Primary Sjogren syndrome; Peripheral neuropathy; Central nervous system; NERVOUS-SYSTEM INVOLVEMENT; SYNDROME-ASSOCIATED NEUROPATHY; CLASSIFICATION CRITERIA; PERIPHERAL NEUROPATHIES; RETROSPECTIVE COHORT; SENSORY NEUROPATHY; DISEASE; DYSFUNCTION; PREVALENCE; COMPLICATIONS;

D O I：

10.1016/j.rdc.2017.06.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The neurologic manifestations of primary Sjogren syndrome are varied and can be divided anatomically into 2 categories: peripheral neuropathies and central nervous system (CNS) conditions. Distal sensory and sensorimotor neuropathies are the most common manifestations of peripheral nerve disease in primary Sjogren syndrome. CNS manifestations associated with primary Sjogren syndrome include focal central lesions; conditions that mimic multiple sclerosis; encephalitis; aseptic meningitis; cerebellar syndromes; movement disorders; and problems with memory, cognition, and depression. The heterogeneity of neurologic manifestations in primary Sjogren syndrome complicates the approach to treatment, which should be directed toward the underlying neuropathologic mechanism.

引用

页码：519 / +

页数：12

共 71 条

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