Venetoclax induced complete remission in extramedullary relapse of AML co-harboring NPM1, TET2, and NRAS mutations after haploidentical hematopoietic stem cell transplantation

被引：8

作者：

Pan, Wenjue ^{[1
]}

Zhao, Xiujie ^{[1
]}

Shi, Wei ^{[2
]}

Jiang, Zhinong ^{[2
]}

Xiao, Haowen ^{[1
,3
]}

机构：

[1] Zhejiang Univ, Sch Med, Dept Hematol, Sir Run Run Shaw Hosp, 3 Qingchun East Rd, Hangzhou 310016, Zhejiang, Peoples R China

[2] Zhejiang Univ, Sch Med, Dept Pathol, Sir Run Run Shaw Hosp, Hangzhou, Peoples R China

[3] Zhejiang Univ, Inst Hematol, Hangzhou, Peoples R China

来源：

LEUKEMIA & LYMPHOMA | 2020年 / 61卷 / 11期

基金：

中国国家自然科学基金;

关键词：

ACUTE MYELOID-LEUKEMIA; BCL-2; INHIBITION; THERAPY; HLA;

D O I：

10.1080/10428194.2020.1779255

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：2756 / 2759

页数：4

共 27 条

[1] Efficacy of the combination of venetoclax and hypomethylating agents in relapsed/refractory acute myeloid leukemia [J].

Aldoss, Ibrahim ;

Yang, Dongyun ;

Aribi, Ahmed ;

Ali, Haris ;

Sandhu, Karamjeet ;

Al Malki, Monzr M. ;

Mei, Matthew ;

Salhotra, Amandeep ;

Khaled, Samer ;

Nakamura, Ryotaro ;

Snyder, David ;

O'Donnell, Margaret ;

Stein, Anthony S. ;

Forman, Stephen J. ;

Marcucci, Guido ;

Pullarkat, Vinod .

HAEMATOLOGICA, 2018, 103 (09) :E404-E407

[2] Extramedullary relapses after allogeneic stem cell transplantation for acute myeloid leukemia: clinical characteristics, incidence, risk factors and outcomes [J].

Alhashim, Noura ;

Aljurf, Mahmoud ;

Hassanein, Mona ;

Chaudhri, Naeem ;

Hashmi, Shahrukh ;

El-Gohary, Ghada ;

Alsharif, Fahad ;

Alsermani, Maamoun ;

Alhumaid, Muhned ;

Al Beihany, Amal ;

Shaheen, Marwan ;

Hanbali, Amr ;

Alfraih, Feras ;

Mohamed, Said ;

Alzahrani, Hazzaa ;

Elhassan, Tusneem ;

Eldali, Abdelmoneim ;

Rasheed, Walid ;

Ahmed, Syed ;

Almohareb, Fahad ;

El Fakih, Riad .

BONE MARROW TRANSPLANTATION, 2018, 53 (07) :838-843

[3] Treatment of relapsed acute myeloid leukemia after allogeneic bone marrow transplantation with chemotherapy followed by G-CSF-primed donor leukocyte infusion: a high incidence of isolated extramedullary relapse [J].

Choi, SJ ;

Lee, JH ;

Kim, S ;

Seol, M ;

Lee, YS ;

Lee, JS ;

Kim, WK ;

Chi, HS ;

Lee, KH .

LEUKEMIA, 2004, 18 (11) :1789-1797

[4] Immune Escape of Relapsed AML Cells after Allogeneic Transplantation [J].

Christopher, M. J. ;

Petti, A. A. ;

Rettig, M. P. ;

Miller, C. A. ;

Chendamarai, E. ;

Duncavage, E. J. ;

Klco, J. M. ;

Helton, N. M. ;

O'Laughlin, M. ;

Fronick, C. C. ;

Fulton, R. S. ;

Wilson, R. K. ;

Wartman, L. D. ;

Welch, J. S. ;

Heath, S. E. ;

Baty, J. D. ;

Payton, J. E. ;

Graubert, T. A. ;

Link, D. C. ;

Walter, M. J. ;

Westervelt, P. ;

Ley, T. J. ;

DiPersio, J. F. .

NEW ENGLAND JOURNAL OF MEDICINE, 2018, 379 (24) :2330-2341

[5] Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML [J].

DiNardo, C. D. ;

Tiong, I. S. ;

Quaglieri, A. ;

MacRaild, S. ;

Loghavi, S. ;

Brown, F. C. ;

Thijssen, R. ;

Pomilio, G. ;

Ivey, A. ;

Salmon, J. M. ;

Glytsou, C. ;

Fleming, S. A. ;

Zhang, Q. ;

Ma, H. ;

Patel, K. P. ;

Kornblau, S. M. ;

Xu, Z. ;

Chua, C. C. ;

Chen, Xufeng ;

Blombery, P. ;

Flensburg, C. ;

Cummings, N. ;

Aifantis, I. ;

Kantarjian, H. ;

Huang, D. C. S. ;

Roberts, A. W. ;

Majewski, I. J. ;

Konopleva, M. ;

Wei, A. H. .

BLOOD, 2020, 135 (11) :791-803

[6] Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia [J].

DiNardo, Courtney D. ;

Pratz, Keith ;

Pullarkat, Vinod ;

Jonas, Brian A. ;

Arellano, Martha ;

Becker, Pamela S. ;

Frankfurt, Olga ;

Konopleva, Marina ;

Wei, Andrew H. ;

Kantarjian, Hagop M. ;

Xu, Tu ;

Hong, Wan-Jen ;

Chyla, Brenda ;

Potluri, Jalaja ;

Pollyea, Daniel A. ;

Letai, Anthony .

BLOOD, 2019, 133 (01) :7-17

[7] Clinical experience with the BCL2-inhibitor venetoclax in combination therapy for relapsed and refractory acute myeloid leukemia and related myeloid malignancies [J].

DiNardo, Courtney D. ;

Rausch, Caitlin R. ;

Benton, Christopher ;

Kadia, Tapan ;

Jain, Nitin ;

Pemmaraju, Naveen ;

Daver, Naval ;

Covert, Wendy ;

Marx, Kayleigh R. ;

Mace, Morgan ;

Jabbour, Elias ;

Cortes, Jorge ;

Garcia-Manero, Guillermo ;

Ravandi, Farhad ;

Bhalla, Kapil N. ;

Kantarjian, Hagop ;

Konopleva, Marina .

AMERICAN JOURNAL OF HEMATOLOGY, 2018, 93 (03) :401-407

[8] Stem cell transplantation from a haploidentical donor versus a genoidentical sister for adult male patients with acute myelogenous leukemia in first remission: A retrospective study from the acute leukemia working party of the European Society for Blood and Marrow Transplantation [J].

Gorin, Norbert-Claude ;

Labopin, Myriam ;

Blaise, Didier ;

de Groot, Marco ;

Soci, Gerard ;

Bourhis, Jean Henri ;

Ciceri, Fabio ;

Polge, Emmanuelle ;

Nagler, Arnon ;

Mohty, Mohamad .

CANCER, 2020, 126 (05) :1004-1015

[9] Venetoclax for Refractory Myeloid Sarcoma [J].

Kanate, Abraham S. ;

Vos, Jeffrey ;

Chargualaf, Michael J. .

JOURNAL OF ONCOLOGY PRACTICE, 2019, 15 (07) :413-+

[10] Graft-versus-leukemia effects of transplantation and donor lymphocytes [J].

Kolb, Hans-Jochem .

BLOOD, 2008, 112 (12) :4371-4383

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