PEG-dendritic block copolymers for biomedical applications

被引：47
作者：
Sousa-Herves, Ana
Riguera, Ricardo
Fernandez-Megia, Eduardo [1 ]
机构：
[1] USC, Dept Organ Chem, Santiago De Compostela 15782, Spain
来源：
NEW JOURNAL OF CHEMISTRY | 2012年 / 36卷 / 02期
关键词：
RING-OPENING POLYMERIZATION; TARGETED GENE DELIVERY; DRUG-DELIVERY; SUPRAMOLECULAR ASSEMBLIES; POLY(ETHYLENE GLYCOL); CLICK CHEMISTRY; IN-VITRO; GLYCOL)-BLOCK-POLY(L-LYSINE) DENDRIMER; PACLITAXEL DELIVERY; DIBLOCK COPOLYMERS;
D O I：
10.1039/c2nj20849k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The incorporation of poly(ethylene glycol) (PEG) chains at the focal point of dendrimers results in customizable platforms where the careful selection of the PEG length, the nature of the peripheral groups, and the structure and generation of the dendritic block entail materials for specific applications in the biomedical field. In this focus article, the synthesis, properties, and biomedical applications of PEG-dendritic block copolymers are discussed with examples in drug and gene delivery, tissue repair, and diagnosis.
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收藏
页码：205 / 210
页数：6
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