2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ)/tert-Butyl Nitrite/Oxygen: A Versatile Catalytic Oxidation System

被引：104

作者：

Shen, Zhenlu ^{[1
]}

Dai, Jialiang ^{[1
]}

Xiong, Jie ^{[1
]}

He, Xijun ^{[1
]}

Mo, Weimin ^{[1
]}

Hu, Baoxiang ^{[1
]}

Sun, Nan ^{[1
]}

Hu, Xinquan ^{[1
,2
]}

机构：

[1] Zhejiang Univ Technol, Coll Chem Engn & Mat Sci, Hangzhou 310014, Zhejiang, Peoples R China

[2] Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2011年 / 353卷 / 16期

基金：

中国国家自然科学基金;

关键词：

alcohols; deprotection; 2; 3-dichloro-5; 6-dicyano-1; 4-benzoquinone (DDQ); oxidation; oxygen; TRANSITION-METAL-FREE; C BOND FORMATION; AEROBIC OXIDATION; HIGHLY EFFICIENT; PROTECTING GROUP; BENZYL ETHERS; SELECTIVE OXIDATION; MOLECULAR-OXYGEN; DDQ; ALCOHOLS;

D O I：

10.1002/adsc.201100429

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A new catalytic oxidation system using catalytic amounts of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) and tert-butyl nitrite with molecular oxygen serving as the environmentally benign, terminal oxidant has been developed. This aerobic catalytic system was established for the selective oxidation of non-sterically hindered benzylic alcohols and electron-rich benzyl methyl ethers, and successfully extended to an application in the oxidative deprotection of PMB ethers to the alcohols in high selectivity.

引用

页码：3031 / 3038

页数：8

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