HupW Protease Specifically Required for Processing of the Catalytic Subunit of the Uptake Hydrogenase in the Cyanobacterium Nostoc sp Strain PCC 7120

被引：16

作者：

Lindberg, Pia ^{[1
]}

Devine, Ellenor ^{[1
]}

Stensjo, Karin ^{[1
]}

Lindblad, Peter ^{[1
]}

机构：

[1] Uppsala Univ, Dept Photochem & Mol Sci, Angstrom Labs, Uppsala, Sweden

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2012年 / 78卷 / 01期

关键词：

ESCHERICHIA-COLI; NICKEL INCORPORATION; NIFE HYDROGENASE; MATURATION; DIVERSITY; NITROGEN; MUTANT;

D O I：

10.1128/AEM.05957-11

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The maturation process of [NiFe] hydrogenases includes a proteolytic cleavage of the large subunit. We constructed a mutant of Nostoc strain PCC 7120 in which hupW, encoding a putative hydrogenase-specific protease, is inactivated. Our results indicate that the protein product of hupW selectively cleaves the uptake hydrogenase in this cyanobacterium.

引用

页码：273 / 276

页数：4

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