Recent developments in analytical applications of quantum dots

被引:117
作者
Kuang, Hua [1 ]
Zhao, Yuan [1 ]
Ma, Wei [1 ]
Xu, Liguang [1 ]
Wang, Libing [1 ,2 ]
Xu, Chuanlai [1 ]
机构
[1] Jiangnan Univ, State Key Lab Food Sci & Technol, Sch Food Sci & Technol, Wuxi 214122, Jiangsu, Peoples R China
[2] Hunan Entry Exit Inspect & Quarantine Bur, Changsha 410001, Hunan, Peoples R China
基金
中国国家自然科学基金;
关键词
Biological detection; Capillary electrophoresis; Chemical detection; Enzyme-linked immunosorbent assay; Fluorescence in-situ hybridization; Fluorescence resonance-energy transfer; Immunoassay; Polymerase chain reaction; Quantum dot; Western blot; RESONANCE ENERGY-TRANSFER; HIGH-QUALITY CDTE; CAPILLARY-ZONE-ELECTROPHORESIS; ANABOLIC-STEROIDS RESIDUES; LINKED-IMMUNOSORBENT-ASSAY; TANDEM MASS-SPECTROMETRY; ANIMAL MUSCLE-TISSUES; LUMINESCENT PROBES; MICROFLUIDIC CHIP; HYBRIDIZATION DETECTION;
D O I
10.1016/j.trac.2011.04.022
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
This review discusses the application of quantum dots (QDs) to chemical and biological detection, for which they have excellent features, particularly size-dependent optical properties. We can summarize the main areas discussed in this review as follows: (1) QDs associated with enzyme-linked immunosorbent assay (ELISA), chip detection and capillary electrophoresis (CE) enhance the sensitivity and the speed of detection of residues; (2) QDs are applied with other techniques, including polymerase chain reaction (PCR), fluorescence resonance-energy transfer (FRET) analysis, fluorescence in-situ hybridization (FISH) and western blot analysis; and, (3) QDs combined with the above techniques can successfully detect DNA and protein. We also cover perspectives and challenges in analytical applications of QDs. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1620 / 1636
页数:17
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