Epoxidation of 1,4-dienyl 3-keto steroidal compounds by dimethyldioxirane: Kinetics

被引：0

作者：

Navarro-Eisenstein, AM ^{[1
]}

Vasquez, PC ^{[1
]}

Franklin, PJ ^{[1
]}

Baumstark, AL ^{[1
]}

机构：

[1] Georgia State Univ, Ctr Biotech & Drug Design, Dept Chem, Atlanta, GA 30303 USA

来源：

HETEROCYCLIC COMMUNICATIONS | 2003年 / 9卷 / 06期

关键词：

ALPHA; BETA-UNSATURATED CARBONYL-COMPOUNDS; DIOXIRANES; OXIDATION; CHEMISTRY; ALKENES;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The epoxidation of 1,4-dienyl 3-keto steroidal compounds by dimethyldioxirane yields mono-epoxides as the primary products as reported in the literature. Kinetic data show the 1,4-dienyl 3-keto system to be at least ten fold more reactive than simple alpha,beta-unsaturated systems.

引用

页码：575 / 578

页数：4