Elemental mass spectrometry for quantitative proteomics

被引:120
作者
Sanz-Medel, Alfredo [1 ]
Montes-Bayon, Maria [1 ]
de la Campa, Maria Del Rosario Fernandez [1 ]
Encinar, Jorge Ruiz [1 ]
Bettmer, Joerg [1 ]
机构
[1] Univ Oviedo, Fac Chem, Dept Phys & Analyt Chem, Oviedo, Spain
关键词
bioanalytical methods; genomics/proteomics; mass spectrometry/inductively coupled plasma mass spectrometry; speciation;
D O I
10.1007/s00216-007-1615-2
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
In the last decade mass-spectrometry-based proteomics has become an indispensable analytical tool for molecular biology, cellular biology and, lately, for the emerging systems biology. This review summarises the evolution and great potential of analytical methods based on elemental mass-spectrometric detection for quantitative proteomic analysis.
引用
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页码:3 / 16
页数:14
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