The Role of Inflammation in Lymphoma

被引：38

作者：

Carbone, Antonino ^{[1
]}

Tripodo, Claudio ^{[2
]}

Carlo-Stella, Carmelo ^{[3
]}

Santoro, Armando ^{[3
]}

Gloghini, Annunziata ^{[4
]}

机构：

[1] IRCCS, Dept Pathol, Ctr Riferimento Oncol Aviano, Ist Nazl Tumori, I-33081 Aviano, Italy

[2] Univ Palermo, Tumor Immunol Unit, Human Pathol Sect, Dept Hlth Sci, Palermo, Italy

[3] Humanitas Clin & Res Ctr, Humanitas Canc Ctr, Dept Hematol & Oncol, Milan, Italy

[4] Fdn IRCCS Ist Nazl Tumori, Dept Diagnost Pathol & Lab Med, Milan, Italy

来源：

INFLAMMATION AND CANCER | 2014年 / 816卷

关键词：

HEPATITIS-C VIRUS; NON-HODGKINS-LYMPHOMA; B-CELL LYMPHOMA; TUMOR-ASSOCIATED MACROPHAGES; II MIXED CRYOGLOBULINEMIA; HEPATOCYTE GROWTH-FACTOR; POOR PATIENT SURVIVAL; REED-STERNBERG CELLS; REGULATORY T-CELLS; FOLLICULAR LYMPHOMA;

D O I：

10.1007/978-3-0348-0837-8_12

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Human lymphomas usually develop in specialized tissue microenvironments characterized by different populations of accessory stromal and lymphoid cells that interact with malignant cells. A clinical role of the tumor microenvironment has recently emerged, bringing new knowledge and suggesting new ideas and targets for treatment. This chapter analyzes the microenvironment in human lymphomas highlighting the role of inflammation in their pathogenesis. Microenvironmental specificity is detailed according to different models including classic Hodgkin lymphoma (HL), follicular lymphoma (FL), diffuse large B-cell lymphoma (DLBCL), peripheral T-cell lymphoma, unspecified and angioimmunoblastic T-cell lymphoma (AITL).

引用

页码：315 / 333

页数：19

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