Isolated skin ulcers due to Mycobacterium tuberculosis in a renal allograft recipient

被引：5

作者：

Ram, Rapur ^{[1
]}

Uppin, Shantveer ^{[1
]}

Swarnalatha, Guditi ^{[1
]}

Desai, Madhav ^{[1
]}

Harke, Megha ^{[1
]}

Prasad, Neela ^{[1
]}

Dakshinamurty, Kaligotla V. ^{[1
]}

机构：

[1] Nizams Inst Med Sci, Dept Nephrol, Hyderabad 500082, Andhra Pradesh, India

来源：

NATURE CLINICAL PRACTICE NEPHROLOGY | 2007年 / 3卷 / 12期

关键词：

cutaneous ulcers; Mycobacterium tuberculosis; renal allograft recipient;

D O I：

10.1038/ncpneph0661

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Background A 27-year-old male renal allograft recipient presented to hospital with isolated skin ulcers on both lower limbs. At presentation, he also had a low-grade continuous fever, malaise and anorexia. Investigations Physical examination, laboratory studies, histopathological examination of tissue biopsy samples from the ulcer edges and ulcer floor, culture of the biopsy tissue, chest radiograph, bone marrow biopsy, abdominal ultrasound, tuberculin skin test and examination of three early morning samples of gastric juice and urine for acid-fast bacilli. Diagnosis Isolated cutaneous ulcers caused by Mycobacterium tuberculosis. Management Four-drug antituberculosis therapy with pyrazinamide, ofloxacin, ethambutol and isoniazid.

引用

页码：688 / 693

页数：6

共 33 条

[1] Prospective randomised trial of isoniazid prophylaxis in renal transplant recipient [J].

Agarwal S.K. ;

Gupta S. ;

Dash S.C. ;

Bhowmik D. ;

Tiwari S.C. .

International Urology and Nephrology, 2004, 36 (3) :425-431

[2] SUCCESSFUL USE OF RIFAMPICIN IN THE TREATMENT OF TUBERCULOSIS IN RENAL-TRANSPLANT PATIENTS IMMUNOSUPPRESSED WITH CYCLOSPORINE [J].

ALSULAIMAN, MH ;

DHAR, JM ;

ALKHADER, AA .

TRANSPLANTATION, 1990, 50 (04) :597-598

[3]

[Anonymous], 1998, MMWR Recomm Rep, V47, P1

[4] Subcutaneous abscesses due to Mycobacterium tuberculosis:: Paradoxical expansion of disease during therapy for miliary tuberculosis [J].

Berg, J ;

Leonard, A ;

Clancy, CJ ;

Nguyen, MH .

CLINICAL INFECTIOUS DISEASES, 1998, 26 (01) :231-232

[5] CUTANEOUS MYCOBACTERIOSIS - ANALYSIS OF 34 CASES WITH A NEW CLASSIFICATION OF THE DISEASE [J].

BEYT, BE ;

ORTBALS, DW ;

SANTACRUZ, DJ ;

KOBAYASHI, GS ;

EISEN, AZ ;

MEDOFF, G .

MEDICINE, 1981, 60 (02) :95-109

[6] INTERACTION OF RIFAMPIN AND GLUCOCORTICOIDS - ADVERSE EFFECT ON RENAL-ALLOGRAFT FUNCTION [J].

BUFFINGTON, GA ;

DOMINGUEZ, JH ;

PIERING, WF ;

HEBERT, LA ;

KAUFFMAN, HM ;

LEMANN, J .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1976, 236 (17) :1958-1960

[7] EFFECT OF RIFAMPICIN ON CYCLOSPORIN-A BLOOD-LEVELS IN A RENAL-TRANSPLANT RECIPIENT [J].

CASSIDY, MJD ;

VANZYLSMIT, R ;

PASCOE, MD ;

SWANEPOEL, CR ;

JACOBSON, JE .

NEPHRON, 1985, 41 (02) :207-208

[8]

CHAN GL, 1992, CLIN TRANSPLANT, V6, P141

[9] Tuberculosis in organ transplant recipients [J].

Chugh, KS ;

Jha, V .

TRANSPLANTATION PROCEEDINGS, 2003, 35 (07) :2676-2677

[10]

*EBPG EXP GROUP RE, 2002, NEPHROL DIAL TRANSPL, V17, pS39

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