SnapShot: Genetics of Parkinson's Disease

被引：63

作者：

Bras, Jose ^{[1
]}

Guerreiro, Rita ^{[1
]}

Hardy, John ^{[1
]}

机构：

[1] UCL, Inst Neurol, Dept Mol Neurosci, London WC1N 1PJ, England

来源：

CELL | 2015年 / 160卷 / 03期

基金：

英国惠康基金; 英国医学研究理事会;

关键词：

RISK LOCI; PATHWAY;

D O I：

10.1016/j.cell.2015.01.019

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：570 / U239

页数：2

共 7 条

[1] Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease [J].

Beilina, Alexandria ;

Rudenko, Iakov N. ;

Kaganovich, Alice ;

Civiero, Laura ;

Chau, Hien ;

Kalia, Suneil K. ;

Kalia, Lorraine V. ;

Lobbestael, Evy ;

Chi, Ruth ;

Ndukwe, Kelechi ;

Ding, Jinhui ;

Nalls, Mike A. ;

Olszewski, Maciej ;

Hauser, David N. ;

Kumaran, Ravindran ;

Lozano, Andres M. ;

Baekelandt, Veerle ;

Greene, Lois E. ;

Taymans, Jean-Marc ;

Greggio, Elisa ;

Cookson, Mark R. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (07) :2626-2631

[2] Use of next-generation sequencing and other whole-genome strategies to dissect neurological disease [J].

Bras, Jose ;

Guerreiro, Rita ;

Hardy, John .

NATURE REVIEWS NEUROSCIENCE, 2012, 13 (07) :453-464

[3] Identifying Consensus Disease Pathways in Parkinson's Disease Using an Integrative Systems Biology Approach [J].

Edwards, Yvonne J. K. ;

Beecham, Gary W. ;

Scott, William K. ;

Khuri, Sawsan ;

Bademci, Guney ;

Tekin, Demet ;

Martin, Eden R. ;

Jiang, Zhijie ;

Mash, Deborah C. ;

Ffrench-Mullen, Jarlath ;

Pericak-Vance, Margaret A. ;

Tsinoremas, Nicholas ;

Vance, Jeffery M. .

PLOS ONE, 2011, 6 (02)

[4] A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinsons disease [J].

Holmans, Peter ;

Moskvina, Valentina ;

Jones, Lesley ;

Sharma, Manu ;

Vedernikov, Alexey ;

Buchel, Finja ;

Sadd, Mohamad ;

Bras, Jose M. ;

Bettella, Francesco ;

Nicolaou, Nayia ;

Simon-Sanchez, Javier ;

Mittag, Florian ;

Gibbs, J. Raphael ;

Schulte, Claudia ;

Durr, Alexandra ;

Guerreiro, Rita ;

Hernandez, Dena ;

Brice, Alexis ;

Stefansson, Hreinn ;

Majamaa, Kari ;

Gasser, Thomas ;

Heutink, Peter ;

Wood, Nicholas W. ;

Martinez, Maria ;

Singleton, Andrew B. ;

Nalls, Michael A. ;

Hardy, John ;

Morris, Huw R. ;

Williams, Nigel M. .

HUMAN MOLECULAR GENETICS, 2013, 22 (05) :1039-1049

[5] Finding the missing heritability of complex diseases [J].

Manolio, Teri A. ;

Collins, Francis S. ;

Cox, Nancy J. ;

Goldstein, David B. ;

Hindorff, Lucia A. ;

Hunter, David J. ;

McCarthy, Mark I. ;

Ramos, Erin M. ;

Cardon, Lon R. ;

Chakravarti, Aravinda ;

Cho, Judy H. ;

Guttmacher, Alan E. ;

Kong, Augustine ;

Kruglyak, Leonid ;

Mardis, Elaine ;

Rotimi, Charles N. ;

Slatkin, Montgomery ;

Valle, David ;

Whittemore, Alice S. ;

Boehnke, Michael ;

Clark, Andrew G. ;

Eichler, Evan E. ;

Gibson, Greg ;

Haines, Jonathan L. ;

Mackay, Trudy F. C. ;

McCarroll, Steven A. ;

Visscher, Peter M. .

NATURE, 2009, 461 (7265) :747-753

[6] Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease [J].

Nalls, Mike A. ;

Pankratz, Nathan ;

Lill, Christina M. ;

Do, Chuong B. ;

Hernandez, Dena G. ;

Saad, Mohamad ;

DeStefano, Anita L. ;

Kara, Eleanna ;

Bras, Jose ;

Sharma, Manu ;

Schulte, Claudia ;

Keller, Margaux F. ;

Arepalli, Sampath ;

Letson, Christopher ;

Edsall, Connor ;

Stefansson, Hreinn ;

Liu, Xinmin ;

Pliner, Hannah ;

Lee, Joseph H. ;

Cheng, Rong ;

Ikram, M. Arfan ;

Ioannidis, John P. A. ;

Hadjigeorgiou, Georgios M. ;

Bis, Joshua C. ;

Martinez, Maria ;

Perlmutter, Joel S. ;

Goate, Alison ;

Marder, Karen ;

Fiske, Brian ;

Sutherland, Margaret ;

Xiromerisiou, Georgia ;

Myers, Richard H. ;

Clark, Lorraine N. ;

Stefansson, Kari ;

Hardy, John A. ;

Heutink, Peter ;

Chen, Honglei ;

Wood, Nicholas W. ;

Houlden, Henry ;

Payami, Haydeh ;

Brice, Alexis ;

Scott, William K. ;

Gasser, Thomas ;

Bertram, Lars ;

Eriksson, Nicholas ;

Foroud, Tatiana ;

Singleton, Andrew B. .

NATURE GENETICS, 2014, 46 (09) :989-+

[7] A generalizable hypothesis for the genetic architecture of disease: pleomorphic risk loci [J].

Singleton, Andrew ;

Hardy, John .

HUMAN MOLECULAR GENETICS, 2011, 20 :R158-R162

← 1 →