Epigenetic regulator ARID1A and stem cell transcription factor SOX9 in the maintenance of pancreatic ductal cell differentiation state and development of intraductal papillary mucinous neoplasia (IPMN) and pancreatic ductal adenocarcinoma (PDAC)

被引：5
作者：
Cui, Naipeng [1 ]
Zhang, Jinsong [2 ]
Huang, Huatian [3 ]
Lu, Lingeng [4 ]
机构：
[1] Hebei Univ, Affiliated Hosp, Dept Breast Surg, Baoding 071000, Peoples R China
[2] St Louis Univ, Sch Med, Dept Pharmacol & Physiol, St Louis, MO 63103 USA
[3] Qian Xi Nan Peoples Hosp, Dept Imaging Diag, Xingyi 652400, Peoples R China
[4] Yale Univ, Yale Canc Ctr, Dept Chron Dis Epidemiol, Sch Med,Yale Sch Publ Hlth,Ctr Biomed Data Sci, 60 Coll St, New Haven, CT 06520 USA
来源：
TRANSLATIONAL CANCER RESEARCH | 2018年 / 7卷
关键词：
ABO BLOOD-GROUP; CANCER; RISK; MUTATIONS; KRAS;
D O I：
10.21037/tcr.2018.07.25
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：S748 / S751
页数：4
相关论文
共 25 条
[1]   KRAS: feeding pancreatic cancer proliferation [J].
Bryant, Kirsten L. ;
Mancias, Joseph D. ;
Kimmelman, Alec C. ;
Der, Channing J. .
TRENDS IN BIOCHEMICAL SCIENCES, 2014, 39 (02) :91-100
[2]   Kras as a key oncogene and therapeutic target in pancreatic cancer [J].
Collins, Meredith A. ;
di Magliano, Marina Pasca .
FRONTIERS IN PHYSIOLOGY, 2014, 4
[3]   Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy [J].
Collisson, Eric A. ;
Sadanandam, Anguraj ;
Olson, Peter ;
Gibb, William J. ;
Truitt, Morgan ;
Gu, Shenda ;
Cooc, Janine ;
Weinkle, Jennifer ;
Kim, Grace E. ;
Jakkula, Lakshmi ;
Feiler, Heidi S. ;
Ko, Andrew H. ;
Olshen, Adam B. ;
Danenberg, Kathleen L. ;
Tempero, Margaret A. ;
Spellman, Paul T. ;
Hanahan, Douglas ;
Gray, Joe W. .
NATURE MEDICINE, 2011, 17 (04) :500-U140
[4]   Targeting mTOR in Pancreatic Ductal Adenocarcinoma [J].
Iriana, Sentia ;
Ahmed, Shahzad ;
Gong, Jun ;
Annamalai, Alagappan Anand ;
Tuli, Richard ;
Hendifar, Andrew Eugene .
FRONTIERS IN ONCOLOGY, 2016, 6
[5]   Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma [J].
Jones, Sian ;
Wang, Tian-Li ;
Shih, Ie-Ming ;
Mao, Tsui-Lien ;
Nakayama, Kentaro ;
Roden, Richard ;
Glas, Ruth ;
Slamon, Dennis ;
Diaz, Luis A., Jr. ;
Vogelstein, Bert ;
Kinzler, Kenneth W. ;
Velculescu, Victor E. ;
Papadopoulos, Nickolas .
SCIENCE, 2010, 330 (6001) :228-231
[6]   SOX9: a stem cell transcriptional regulator of secreted niche signaling factors [J].
Kadaja, Meelis ;
Keyes, Brice E. ;
Lin, Mingyan ;
Pasolli, Amalia ;
Genander, Maria ;
Polak, Lisa ;
Stokes, Nicole ;
Zheng, Deyou ;
Fuchs, Elaine .
GENES & DEVELOPMENT, 2014, 28 (04) :328-341
[7]   ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice [J].
Kimura, Yoshito ;
Fukuda, Akihisa ;
Ogawa, Satoshi ;
Maruno, Takahisa ;
Takada, Yutaka ;
Tsuda, Motoyuki ;
Hiramatsu, Yukiko ;
Araki, Osamu ;
Nagao, Munemasa ;
Yoshikawa, Takaaki ;
Ikuta, Kozo ;
Yoshioka, Takuto ;
Wang, Zong ;
Akiyama, Haruhiko ;
Wright, Christopher V. ;
Takaori, Kyoichi ;
Uemoto, Shinji ;
Chiba, Tsutomu ;
Seno, Hiroshi .
GASTROENTEROLOGY, 2018, 155 (01) :194-+
[8]  
Lennerz Jochen K, 2015, Oncologist, V20, pe8, DOI 10.1634/theoncologist.2014-0408
[9]   Arid1a restrains Kras-dependent changes in acinar cell identity [J].
Livshits, Geulah ;
Alonso-Curbelo, Direna ;
Morris, John P. ;
Koche, Richard ;
Saborowski, Michael ;
Wilkinson, John Erby ;
Lowe, Scott W. .
ELIFE, 2018, 7
[10]   Frequency of K-ras mutations in pancreatic intraductal neoplasias associated with pancreatic ductal adenocarcinorna and chronic pancreatitis:: A meta-analysis [J].
Löhr, M ;
Klöppel, G ;
Maisonneuve, P ;
Lowenfels, AB ;
Lüttges, J .
NEOPLASIA, 2005, 7 (01) :17-23
123