Diamond micro system for bio-chemistry

This work illustrates the potential of diamond micro system technologies progressively developed in the Last years for an application in the bio-chemical field, A diamond micro reactor system based on a novel integration concept is presented and the role of diamond in this generic system is described. It consists of reaction chambers with removable bottom and integrated micro dosage elements allowing the ejection and mixture of two different fluids onto the removable bottom substrate. As an example, this system is used in a novel DNA-synthesis cycle. In this application the diamond micro reactor system combined with a specifically designed chemistry for the DNA-synthesis enables the parallel production of DNA-chain-clusters with individual sequence arranged in an array (DNA-Chip). (C) 2001 Elsevier Science B.V. All rights reserved.