Oocyte Vitrification for Fertility Preservation in Women with Benign Gynecologic Disease: French Clinical Practice Guidelines Developed by a Modified Delphi Consensus Process

被引:7
作者
Courbiere, Blandine [1 ,2 ]
Le Roux, Enora [3 ,4 ]
d'Argent, Emmanuelle Mathieu [5 ]
Torre, Antoine [6 ]
Patrat, Catherine [7 ]
Poncelet, Christophe [8 ,9 ]
Montagut, Jacques [10 ]
Gremeau, Anne-Sophie [11 ]
Creux, Helene [12 ]
Peigne, Maeliss [9 ,13 ]
Chanavaz-Lacheray, Isabella [14 ]
Dirian, Lara [15 ]
Fritel, Xavier [16 ,17 ]
Pouly, Jean-Luc [18 ]
Fauconnier, Arnaud [19 ,20 ]
机构
[1] Hop La Conception, AP HM, Dept Gynecol Obstet & Reprod Med, F-13005 Marseille, France
[2] Aix Marseille Univ, Avignon Univ, CNRS, IMBE,IRD, F-13005 Marseille, France
[3] Nord Univ Paris, Hop Univ Robert Debre, AP HP, Unite Epidemiol Clin,INSERM,CIC 1426, F-75019 Paris, France
[4] Univ Paris, INSERM, ECEVE UMR 1123, F-75019 Paris, France
[5] Univ Pierre & Marie Curie Paris 6, Hop Tenon, AP HP,Ctr Expert Endometriose C3E, CHU Tenon,Dept Gynecol Obstetr & Reprod Med,GRC6, 4 Rue Chine, F-75020 Paris, France
[6] CHU Rouen, Dept Gynecol Obstetr & Reprod Med, 37 Bd Gambetta, F-76000 Rouen, France
[7] Univ Paris, APHP Ctr, Serv Biol Reprod CECOS, Site Cochin,INSERM,U1016, F-75014 Paris, France
[8] CH Rene Dubos, Dept Gynecol Obstetr, UFR SMBH Leonard de Vinci, F-95000 Cergy Pontoise, France
[9] Univ Sorbonne Paris Nord Paris 13, F-93200 St Denis, France
[10] Inst Francophone Rech & Etud Appl Reprod, Ifreares Toulouse, F-31000 Toulouse, France
[11] Univ Hosp Clermont Ferrand, Dept Gynecol Surg & IVF, F-63000 Clermont Ferrand, France
[12] Clin St Roch, Dept Gynecol Obstetr & Reprod Med, F-34000 Montpellier, France
[13] Hop Jean Verdier, AP HP, Dept Reprod Med & Fertil Preservat, F-93143 Bondy, France
[14] Clin Tivoli Ducos, Ctr Endometriose, F-33000 Bordeaux, France
[15] Assoc Francaise Lutte Endometriose, EndoFrance, F-70190 Tresilley, France
[16] CHU Poitiers, Dept Gynecol Obstetr & Reprod Med, F-86000 Poitiers, France
[17] Inserm CIC P 1402, F-86021 Poitiers, France
[18] CH Moulins Yzeure, Dept Gynecol Obstetr, F-03000 Moulins, France
[19] CHI Poissy St Germain Laye, Dept Gynecol & Obstet, F-78300 Poissy, France
[20] Paris Saclay Univ, Res Unit 7285 Risk & Safety Clin Med Women & Peri, F-78300 Poissy, France
关键词
fertility preservation; oocyte vitrification; benign gynecologic disease; modified Delphi method; consensus study; ENDOMETRIOSIS; HORMONE; AGE;
D O I
10.3390/jcm10173810
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
International guidelines are published to provide standardized information and fertility preservation (FP) care for adults and children. The purpose of the study was to conduct a modified Delphi process for generating FP guidelines for BGD. A steering committee identified 42 potential FP practices for BGD. Then 114 key stakeholders were asked to participate in a modified Delphi process via two online survey rounds and a final meeting. Consensus was reached for 28 items. Among them, stakeholders rated age-specific information concerning the risk of diminished ovarian reserve after surgery as important but rejected proposals setting various upper and lower age limits for FP. All women should be informed about the benefit/risk balance of oocyte vitrification-in particular about the likelihood of live birth according to age. FP should not be offered in rASRM stages I and II endometriosis without endometriomas. These guidelines could be useful for gynecologists to identify situations at risk of infertility and to better inform women with BGDs who might need personalized counseling for FP.
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页数:17
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