Small molecule targeting of gβγ reduces β-adrenergic receptor desensitization and normalizes cardiac dysfunction in an acute heart failure model

被引：0

作者：

Casey, Liam ^{[1
]}

Nwakanma, Frances ^{[1
]}

Vorobiof, Gabriel ^{[1
]}

Dunaevsky, Olga ^{[1
]}

Smrcka, Alan V. ^{[1
]}

Blaxall, Burns C. ^{[1
]}

机构：

[1] Univ Rochester, Med Ctr, Rochester, NY 14627 USA

来源：

CIRCULATION | 2007年 / 116卷 / 16期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

1268

引用

页码：258 / 258

页数：1

共 43 条

[41] B-blocker therapy in heart failure reduces migratory and proliferative properties of primarily cultured failing cardiac fibroblasts via reduction of g protein-coupled receptor kinase-2 expression [J].

Komici, K. ;

Cannavo, A. ;

Gambino, G. ;

De Lucia, C. ;

D'Amico, M. L. ;

Liccardo, D. ;

Petraglia, L. ;

Formisano, R. ;

Lania, G. ;

Barone, M. V. ;

Leosco, D. ;

Ferrara, N. ;

Rengo, G. .

CARDIOVASCULAR RESEARCH, 2016, 111 :S52-S52

[42] Alpha 2a adrenergic receptor antagonism abrogates innate immune dysfunction and hepatic inflammatory cytokine generation in a rodent model of Acute-on-Chronic Liver Failure (AoCLF): Proof of concept for a new target for therapy [J].

Sharma, Vikram ;

Soeda, Junpei ;

MacNaughtan, Jane ;

Habtesion, Abeba ;

Leckie, Pamela ;

Davies, Nathan ;

Jalan, Rajiv ;

Mookerjee, Rajeshwar .

HEPATOLOGY, 2014, 60 :488A-488A

[43] AAV9 Mediated G-protein Receptor Inhibition by Beta-adrenoreceptor Kinase Carboxyl-terminus Ameliorates Cardiac Function in a Pig Model Chronic Heart Failure [J].

Thormann, Michael ;

Lebherz, Corinna ;

Hinkel, Rabea ;

Wuchrer, Alexander ;

El-Aouni, Chiraz ;

Kupatt, Christian ;

Mueller, Oliver ;

Kleinschmidt, Juergen ;

Boekstegers, Peter .

CIRCULATION, 2009, 120 (18) :S900-S900

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