Small molecule targeting of gβγ reduces β-adrenergic receptor desensitization and normalizes cardiac dysfunction in an acute heart failure model

被引：0

作者：

Casey, Liam ^{[1
]}

Nwakanma, Frances ^{[1
]}

Vorobiof, Gabriel ^{[1
]}

Dunaevsky, Olga ^{[1
]}

Smrcka, Alan V. ^{[1
]}

Blaxall, Burns C. ^{[1
]}

机构：

[1] Univ Rochester, Med Ctr, Rochester, NY 14627 USA

来源：

CIRCULATION | 2007年 / 116卷 / 16期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

1268

引用

页码：258 / 258

页数：1

共 43 条

[21] Endothelial protein tyrosine phosphatase 1b deficiency reduces both endothelial and cardiac dysfunction of in a mouse model of heart failure
Maupoint, J.
Bouhzam, N.
Gomez, E.
Besnier, M.
Henry, J. P.
Mulder, P.
Richard, V.
EUROPEAN HEART JOURNAL, 2014, 35 : 508 - 508
[22] Endothelial protein tyrosine phosphatase 1B deficiency reduces both endothelial and cardiac dysfunction of in a mouse model of heart failure
Maupoint, J.
Bouhzam, N.
Gomez, E.
Besnier, M.
Henry, J. P.
Mulder, P.
Richard, V.
FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2013, 27 : 4 - 5
[23] Treatment with ranolazine attenuates cardiac hypertrophy and contractile dysfunction in a murine model of heart failure induced by chronic beta1-adrenergic stimulation
Primessnig, U.
Schoenleitner, P.
Schmidt, A.
Hoell, A.
Wakula, P.
Engelhardt, S.
Antoons, G.
Pieske, B.
Heinzel, F. R.
EUROPEAN HEART JOURNAL, 2015, 36 : 666 - 666
[24] Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure*
Bosch, Lena
de Haan, Judith
Seijkens, Tom
van Tiel, Claudia
Brans, Maike
Pasterkamp, Gerard
Lutgens, Esther
de Jager, Saskia
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2019, 279 : 141 - 144
[25] Acute effects of beta 1-selective and nonselective beta-adrenergic receptor blockade on cardiac sympathetic activity in congestive heart failure
Newton, GE
Parker, JD
CIRCULATION, 1996, 94 (03) : 353 - 358
[26] Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure
Bosch, L.
De Haan, J. J.
Seijkens, T.
Van Tiel, C.
Brans, M.
Pasterkamp, G.
Lutgens, E.
De Jager, S. C. A.
EUROPEAN HEART JOURNAL, 2018, 39 : 588 - 588
[27] Caloric restriction ameliorates cardiac function, sympathetic cardiac innervation and beta-adrenergic receptor signaling in an experimental model of post-ischemic heart failure
De Lucia, C.
Gambino, G.
Petraglia, L.
Elia, A.
Komici, K.
Femminella, G. D.
D'amico, M. L.
Pagano, G.
Cannavo, A.
Liccardo, D.
Koch, W. J.
Nolano, M.
Leosco, D.
Ferrara, N.
Rengo, G.
CARDIOVASCULAR RESEARCH, 2016, 111 : S112 - S112
[28] β3-Adrenergic receptor blockade reduces mortality in endotoxin-induced heart failure by suppressing induced nitric oxide synthase and saving cardiac metabolism
Kawaguchi, Satoshi
Okada, Motoi
Ijiri, Eriko
Koga, Daisuke
Watanabe, Tsuyoshi
Hayashi, Kentaro
Kashiwagi, Yuta
Fujita, Satoshi
Hasebe, Naoyuki
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2020, 318 (02): : H283 - H294
[29] Targeting the β-Adrenergic Receptor System Through G-Protein-Coupled Receptor Kinase 2: A New Paradigm for Therapy and Prognostic Evaluation in Heart Failure From Bench to Bedside
Rengo, Giuseppe
Perrone-Filardi, Pasquale
Femminella, Grazia D.
Liccardo, Daniela
Zincarelli, Carmela
de Lucia, Claudio
Pagano, Gennaro
Marsico, Fabio
Lymperopoulos, Anastasios
Leosco, Dario
CIRCULATION-HEART FAILURE, 2012, 5 (03) : 385 - 391
[30] Elabela, a Novel Apj-receptor Agonist, Improves Fluid Homeostasis and Reduces Cardio-renal Dysfunction During Acute Heart Failure (AHF)
Coquerel, David
Sainsily, Xavier
Chagnon, Frederic
Murza, Alexandre
Dumont, Lauralyne
Dumaine, Robert
Sarret, Philippe
Marsault, Eric
Salvail, Dan
Auger-Messier, Mannix
Lesur, Olivier
CIRCULATION, 2016, 134

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