A geometric analysis of the SIRS epidemiological model on a homogeneous network

被引:20
作者
Jardon-Kojakhmetov, Hildeberto [1 ]
Kuehn, Christian [2 ]
Pugliese, Andrea [3 ]
Sensi, Mattia [3 ]
机构
[1] Univ Groningen, Fac Sci & Engn, Groningen, Netherlands
[2] Tech Univ Munich, Dept Math, Munich, Germany
[3] Univ Trento, Trento, Italy
关键词
Fast-slow system; Epidemic model; Non-standard form; Epidemics on networks; Bifurcation analysis; SINGULAR PERTURBATION PROBLEMS; EXCHANGE LEMMAS; DYNAMICS; CELL;
D O I
10.1007/s00285-021-01664-5
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We study a fast-slow version of an SIRS epidemiological model on homogeneous graphs, obtained through the application of the moment closure method. We use GSPT to study the model, taking into account that the infection period is much shorter than the average duration of immunity. We show that the dynamics occurs through a sequence of fast and slow flows, that can be described through 2-dimensional maps that, under some assumptions, can be approximated as 1-dimensional maps. Using this method, together with numerical bifurcation tools, we show that the model can give rise to periodic solutions, differently from the corresponding model based on homogeneous mixing.
引用
收藏
页数:38
相关论文
共 44 条
[21]   Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period [J].
Kissler, Stephen M. ;
Tedijanto, Christine ;
Goldstein, Edward ;
Grad, Yonatan H. ;
Lipsitch, Marc .
SCIENCE, 2020, 368 (6493) :860-+
[22]   Geometric analysis of the Goldbeter minimal model for the embryonic cell cycle [J].
Kosiuk, Ilona ;
Szmolyan, Peter .
JOURNAL OF MATHEMATICAL BIOLOGY, 2016, 72 (05) :1337-1368
[23]  
Kuehn C., 2015, Applied Mathematical Sciences
[24]   Moment Closure-A Brief Review [J].
Kuehn, Christian .
CONTROL OF SELF-ORGANIZING NONLINEAR SYSTEMS, 2016, :253-271
[25]   Multiscale Geometry of the Olsen Model and Non-classical Relaxation Oscillations [J].
Kuehn, Christian ;
Szmolyan, Peter .
JOURNAL OF NONLINEAR SCIENCE, 2015, 25 (03) :583-629
[26]   On decomposing mixed-mode oscillations and their return maps [J].
Kuehn, Christian .
CHAOS, 2011, 21 (03)
[27]   Natural immune boosting in pertussis dynamics and the potential for long-term vaccine failure [J].
Lavine, Jennie S. ;
King, Aaron A. ;
Bjornstad, Ottar N. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (17) :7259-7264
[28]   Exchange lemmas for singular perturbation problems with certain turning points [J].
Liu, WS .
JOURNAL OF DIFFERENTIAL EQUATIONS, 2000, 167 (01) :134-180
[29]   Stochastic descriptors in an SIR epidemic model for heterogeneous individuals in small networks [J].
Lopez-Garcia, M. .
MATHEMATICAL BIOSCIENCES, 2016, 271 :42-61
[30]   Reduction of a model of an excitable cell to a one-dimensional map [J].
Medvedev, GS .
PHYSICA D-NONLINEAR PHENOMENA, 2005, 202 (1-2) :37-59