A spectroscopic tool based on an interference filter and birefringent prisms: demonstration of detection of 5-aminolaevulinic acid-induced protoporphyrin IX fluorescence

被引：4
|
作者：
O'Dwyer, M [1 ]
Nadeau, V [1 ]
Padgett, M [1 ]
机构：
[1] Univ Glasgow, Dept Phys & Astron, Glasgow G12 8QQ, Lanark, Scotland
来源：
JOURNAL OF PHYSICS D-APPLIED PHYSICS | 2003年 / 36卷 / 14期
关键词：
D O I：
10.1088/0022-3727/36/14/308
中图分类号：
O59 [应用物理学];
学科分类号：
摘要：
We describe a differential fluorescence detection system that consists of a 405 nm diode laser for fluorescence excitation, a bifurcated fibre for delivery of light to and collection of light from tissue, birefringent prisms and a tilted filter. This instrument is optimized for the selective detection of protoporphyrin IX fluorescence and autofluorescence from tissue, and its effectiveness demonstrated using low excitation light levels (0.7 mW cm(-2)).
引用
收藏
页码：1703 / 1706
页数：4
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