Antibody-Drug Conjugates: Perspectives and Characterization

被引:0
|
作者
Moore, Rowan E. [1 ]
Broster, Kelly [2 ]
Cook, Ken [2 ]
D'Silva, Kyle [2 ]
Niederkofler, Eric [2 ]
Bailey, Aaron O. [2 ]
Bones, Jonathan [3 ]
Dong, Michael W. [4 ,5 ,6 ,7 ]
机构
[1] Thermo Fisher Sci, Bio Pharma Applicat Dev Team, Hemel Hempstead, England
[2] Thermo Fisher Sci, Hemel Hempstead, England
[3] NIBRT, Blackrock, Co Dublin, Ireland
[4] MWD Consulting, Norwalk, CT 06851 USA
[5] Genentech Inc, San Francisco, CA 94080 USA
[6] Purdue Pharma, Stamford, CT USA
[7] PerkinElmer, Appl Biosyst, Waltham, MA USA
关键词
EXCHANGE MASS-SPECTROMETRY; CHROMATOGRAPHY; CHALLENGES;
D O I
暂无
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
This instalment of "Perspectives in Modern HPLC" provides an overview of antibody-drug conjugates (ADCs) as a new class of biotherapeutics and describes their analytical characterization for quality assessment with examples from extensive applications libraries.
引用
收藏
页码:332 / 343
页数:12
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