Antibody-Drug Conjugates: Perspectives and Characterization

被引：0

作者：

Moore, Rowan E. ^{[1
]}

Broster, Kelly ^{[2
]}

Cook, Ken ^{[2
]}

D'Silva, Kyle ^{[2
]}

Niederkofler, Eric ^{[2
]}

Bailey, Aaron O. ^{[2
]}

Bones, Jonathan ^{[3
]}

Dong, Michael W. ^{[4
,5
,6
,7
]}

机构：

[1] Thermo Fisher Sci, Bio Pharma Applicat Dev Team, Hemel Hempstead, England

[2] Thermo Fisher Sci, Hemel Hempstead, England

[3] NIBRT, Blackrock, Co Dublin, Ireland

[4] MWD Consulting, Norwalk, CT 06851 USA

[5] Genentech Inc, San Francisco, CA 94080 USA

[6] Purdue Pharma, Stamford, CT USA

[7] PerkinElmer, Appl Biosyst, Waltham, MA USA

来源：

LC GC EUROPE | 2018年 / 31卷 / 06期

关键词：

EXCHANGE MASS-SPECTROMETRY; CHROMATOGRAPHY; CHALLENGES;

D O I：

暂无

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

This instalment of "Perspectives in Modern HPLC" provides an overview of antibody-drug conjugates (ADCs) as a new class of biotherapeutics and describes their analytical characterization for quality assessment with examples from extensive applications libraries.

引用

页码：332 / 343

页数：12

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