MARIMO cells harbor a CALR mutation but are not dependent on JAK2/STAT5 signaling

被引：31
作者：
Kollmann, K. [1 ,2 ]
Nangalia, J. [1 ,2 ,3 ,4 ]
Warsch, W. [1 ,2 ]
Quentmeier, H. [5 ]
Bench, A. [4 ]
Boyd, E. [4 ]
Scott, M. [4 ]
Drexler, H. G. [5 ]
Green, A. R. [1 ,2 ,4 ]
机构：
[1] Univ Cambridge, Wellcome Trust MRC Stem Cell Inst, Cambridge Inst Med Res, Cambridge, England
[2] Univ Cambridge, Dept Haematol, Cambridge, England
[3] Wellcome Trust Sanger Inst, Cambridge, England
[4] Cambridge Univ Hosp NHS Fdn Trust, Cambridge, England
[5] German Collect Microorganisms & Cell Cultures, Leibniz Inst DSMZ, Braunschweig, Germany
来源：
LEUKEMIA | 2015年 / 29卷 / 02期
关键词：
MYELOPROLIFERATIVE NEOPLASMS; ESSENTIAL THROMBOCYTHEMIA; MYELOFIBROSIS; RETICULUM; JAK2; CALRETICULIN; INHIBITOR;
D O I：
10.1038/leu.2014.285
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：494 / 497
页数：5
相关论文
共 50 条
  • [41] Ruxolitinib can cause weight gain by blocking leptin signaling in the brain via JAK2/STAT3
    Molle, Nicole
    Krichevsky, Spencer
    Kermani, Pouneh
    Silver, Richard T.
    Ritchie, Ellen
    Scandura, Joseph M.
    BLOOD, 2020, 135 (13) : 1062 - 1066
  • [42] Human growth disorders associated with impaired GH action: Defects in STAT5B and JAK2
    Hwa, Vivian
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2021, 519
  • [43] JAK2 V617F Mutation in Endothelial Cells of Patients with Atherosclerotic Carotid Disease
    Diz-Kucukkaya, Reyhan
    Iyigun, Taner
    Albayrak, Ozgur
    Eker, Candan
    Gunel, Tuba
    TURKISH JOURNAL OF HEMATOLOGY, 2024, 41 (03) : 167 - 174
  • [44] Spleen endothelial cells from patients with myelofibrosis harbor the JAK2V617F mutation
    Rosti, Vittorio
    Villani, Laura
    Riboni, Roberta
    Poletto, Valentina
    Bonetti, Elisa
    Tozzi, Lorenzo
    Bergamaschi, Gaetano
    Catarsi, Paolo
    Dallera, Elena
    Novara, Francesca
    Massa, Margherita
    Campanelli, Rita
    Fois, Gabriela
    Peruzzi, Benedetta
    Lucioni, Marco
    Guglielmelli, Paola
    Pancrazzi, Alessandro
    Fiandrino, Giacomo
    Zuffardi, Orsetta
    Magrini, Umberto
    Paulli, Marco
    Vannucchi, Alessandro M.
    Barosi, Giovanni
    BLOOD, 2013, 121 (02) : 360 - 368
  • [45] Hepatitis B virus X protein modulates apoptosis in human renal proximal tubular epithelial cells by activating the JAK2/STAT3 signaling pathway
    He, Ping
    Zhang, Dan
    Li, Hong
    Yang, Xu
    Li, Detian
    Zhai, Yongzhen
    Ma, Li
    Feng, Guohe
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2013, 31 (05) : 1017 - 1029
  • [46] JAK/STAT signaling pathway affects CCR5 expression in human CD4+ T cells
    Wang, Lingyun
    Yukselten, Yunus
    Nuwagaba, Julius
    Sutton, Richard E.
    SCIENCE ADVANCES, 2024, 10 (12)
  • [47] JAK2 V617F stimulates proliferation of erythropoietin-dependent erythroid progenitors and delays their differentiation by activating Stat1 and other nonerythroid signaling pathways
    Shi, Jiahai
    Yuan, Bingbing
    Hu, Wenqian
    Lodish, Harvey
    EXPERIMENTAL HEMATOLOGY, 2016, 44 (11) : 1044 - 1058
  • [48] MicroRNA-204-5p Deficiency within the vmPFC Region Contributes to Neuroinflammation and Behavioral Disorders via the JAK2/STAT3 Signaling Pathway in Rats
    Chen, Xiao
    Gan, Yeting
    Zhang, Kaiqi
    Wu, Yuhan
    Li, Ye
    Lan, Tian
    Zhuang, Xianghua
    Chen, Shihong
    Yu, Shuyan
    ADVANCED SCIENCE, 2025,
  • [49] Activation of the tissue factor-dependent extrinsic pathway and its relation to JAK2 V617F mutation status in patients with essential thrombocythemia
    Gadomska, Grazyna
    Stankowska, Katarzyna
    Boinska, Joanna
    Bartoszewska-Kubiak, Alicja
    Haus, Olga
    Rosc, Danuta
    BLOOD COAGULATION & FIBRINOLYSIS, 2016, 27 (07) : 817 - 821
  • [50] Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2-dependent adult T-cell leukemia
    Zhang, Meili
    Griner, Lesley A. Mathews
    Ju, Wei
    Duveau, Damien Y.
    Guha, Rajarshi
    Petrus, Michael N.
    Wen, Bernard
    Maeda, Michiyuki
    Shinn, Paul
    Ferrer, Marc
    Conlon, Kevin D.
    Bamford, Richard N.
    O'Shea, John J.
    Thomas, Craig J.
    Waldmann, Thomas A.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112 (40) : 12480 - 12485
12345