Single-cell RNA sequencing identifies macrophage transcriptional heterogeneities in granulomatous diseases

被引:15
作者
Liao, Shu-Yi [1 ]
Atif, Shaikh M. [2 ]
Mould, Kara [1 ]
Konigsberg, Iain R. [2 ]
Fu, Rui [3 ]
Davidson, Elizabeth [2 ]
Li, Li [1 ,2 ]
Fontenot, Andrew P. [2 ,4 ]
Maier, Lisa A. [1 ,2 ,5 ]
Yang, Ivana V. [2 ,6 ]
机构
[1] Natl Jewish Hlth, Dept Med, Denver, CO USA
[2] Univ Colorado Anschutz Med Campus, Dept Med, 12700 E 19th Ave, Aurora, CO 80045 USA
[3] Univ Colorado Anschutz Med Campus, RNA Biosci Initiat, Aurora, CO USA
[4] Univ Colorado Anschutz Med Campus, Dept Immunol & Microbiol, Aurora, CO USA
[5] Colorado Sch Publ Hlth, Dept Environm & Occupat Hlth, Aurora, CO USA
[6] Colorado Sch Publ Hlth, Dept Epidemiol, Aurora, CO USA
关键词
SARCOIDOSIS; EXPRESSION;
D O I
10.1183/13993003.03794-2020
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
引用
收藏
页数:4
相关论文
共 17 条
[1]   Diverse macrophage populations mediate acute lung inflammation and resolution [J].
Aggarwal, Neil R. ;
King, Landon S. ;
D'Alessio, Franco R. .
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2014, 306 (08) :L709-L725
[2]   An Official American Thoracic Society Statement: Diagnosis and Management of Beryllium Sensitivity and Chronic Beryllium Disease Executive Summary [J].
Balmes, John R. ;
Abraham, Jerrold L. ;
Dweik, Raed A. ;
Fireman, Elizabeth ;
Fontenot, Andrew P. ;
Maier, Lisa A. ;
Muller-Quernheim, Joachim ;
Ostiguy, Gaston ;
Pepper, Lewis D. ;
Saltini, Cesare ;
Schuler, Christine R. ;
Takaro, Tim K. ;
Wambach, Paul F. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2014, 190 (10) :1177-1185
[3]   HSP70-hom gene single nucleotide (+2763 G/A and+2437 C/T) polymorphisms in sarcoidosis [J].
Bogunia-Kubik, K ;
Koscinska, K ;
Suchnicki, K ;
Lange, A .
INTERNATIONAL JOURNAL OF IMMUNOGENETICS, 2006, 33 (02) :135-140
[4]   Integrating single-cell transcriptomic data across different conditions, technologies, and species [J].
Butler, Andrew ;
Hoffman, Paul ;
Smibert, Peter ;
Papalexi, Efthymia ;
Satija, Rahul .
NATURE BIOTECHNOLOGY, 2018, 36 (05) :411-+
[5]   Bronchoalveolar lavage cells from sarcoidosis patients and healthy controls can efficiently present antigens - Introduction [J].
Grunewald, J ;
Eklund, A ;
Wigzell, H ;
Van Meijgaarden, KE ;
Ottenhoff, THM .
JOURNAL OF INTERNAL MEDICINE, 1999, 245 (04) :353-357
[6]   Activator protein-1 activation in acute lung injury [J].
Guo, RF ;
Lentsch, AB ;
Sarma, JV ;
Sun, L ;
Riedemann, NC ;
McClintock, SD ;
McGuire, SR ;
Van Rooijen, N ;
Ward, PA .
AMERICAN JOURNAL OF PATHOLOGY, 2002, 161 (01) :275-282
[7]  
HRYCAJ P, 1995, SARCOIDOSIS, V12, P124
[8]   Beryllium-induced lung disease exhibits expression profiles similar to sarcoidosis [J].
Li, Li ;
Silveira, Lori J. ;
Hamzeh, Nabeel ;
Gillespie, May ;
Mroz, Peggy M. ;
Mayer, Annyce S. ;
Fingerlin, Tasha E. ;
Maier, Lisa A. .
EUROPEAN RESPIRATORY JOURNAL, 2016, 47 (06) :1797-1808
[9]   Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19 [J].
Liao, Mingfeng ;
Liu, Yang ;
Yuan, Jing ;
Wen, Yanling ;
Xu, Gang ;
Zhao, Juanjuan ;
Cheng, Lin ;
Li, Jinxiu ;
Wang, Xin ;
Wang, Fuxiang ;
Liu, Lei ;
Amit, Ido ;
Zhang, Shuye ;
Zhang, Zheng .
NATURE MEDICINE, 2020, 26 (06) :842-+
[10]   Kruppel-like factor 4 regulates macrophage polarization [J].
Liao, Xudong ;
Sharma, Nikunj ;
Kapadia, Fehmida ;
Zhou, Guangjin ;
Lu, Yuan ;
Hong, Hong ;
Paruchuri, Kaavya ;
Mahabeleshwar, Ganapati H. ;
Dalmas, Elise ;
Venteclef, Nicolas ;
Flask, Chris A. ;
Kim, Julian ;
Doreian, Bryan W. ;
Lu, Kurt Q. ;
Kaestner, Klaus H. ;
Hamik, Anne ;
Clement, Karine ;
Jain, Mukesh K. .
JOURNAL OF CLINICAL INVESTIGATION, 2011, 121 (07) :2736-2749