Glutathione and pH serial responsive functional mesoporous silica nanoparticles for drug delivery

被引：1
作者：
He, Liang [1 ,2 ]
Nan, Xueyan [1 ]
Wang, Tong [1 ]
Bai, Pengli [1 ,3 ,4 ]
机构：
[1] Chinese Acad Sci, Suzhou Inst Biomed Engn & Technol, Suzhou 215163, Peoples R China
[2] Qingdao Univ, Coll Chem & Chem Engn, Inst Biomed Mat & Engn, Qingdao 266071, Peoples R China
[3] Univ Sci & Technol China, Hefei 230026, Peoples R China
[4] Tianjin Guokeyigong Sci & Technol Dev Co Ltd, Tianjin 300399, Peoples R China
来源：
MICRO & NANO LETTERS | 2020年 / 15卷 / 05期
关键词：
CHITOSAN NANOPARTICLES; GRAPHENE OXIDE; CARBON DOTS; CO-DELIVERY; CANCER; NANOCARRIERS; DOXORUBICIN; THERAPY;
D O I：
10.1049/mnl.2019.0317
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
In this work, a novel glutathione and pH serial dual-responsive drug delivery system has been developed, which was constructed with chitosan (CS), carbon dots (CDs) and hyaluronic acid (HA) modified the mesoporous silica nanoparticles (MSNs). The system showed excellent drug loading efficiency, controlled release and targeted delivery. In addition, the platform (MSN-CS@HA-CDs) exhibited fluorescence imaging property. The prepared drug delivery system appeared to be a promising cancer treatment platform.
引用
收藏
页码：291 / 295
页数：5
相关论文
共 50 条
[41]   A pH/ROS-responsive, tumor-targeted drug delivery system based on carboxymethyl chitin gated hollow mesoporous silica nanoparticles for anti-tumor chemotherapy [J].
Ding, Xiao ;
Yu, Wenjie ;
Wan, Yunfeng ;
Yang, Mingyue ;
Hua, Chenghuan ;
Peng, Na ;
Liu, Yi .
CARBOHYDRATE POLYMERS, 2020, 245
[42]   Multifunctional Redox-Responsive Mesoporous Silica Nanoparticles for Efficient Targeting Drug Delivery and Magnetic Resonance Imaging [J].
Chen, Liang ;
Zhou, Xiaojun ;
Nie, Wei ;
Zhang, Qianqian ;
Wang, Weizhong ;
Zhang, Yanzhong ;
He, Chuanglong .
ACS APPLIED MATERIALS & INTERFACES, 2016, 8 (49) :33829-33841
[43]   Recent advance in functionalized mesoporous silica nanoparticles with stimuli-responsive polymer brush for controlled drug delivery [J].
Alfhaid, Latifah Hamad K. .
SOFT MATERIALS, 2022, 20 (03) :364-378
[44]   Heat shock responsive drug delivery system based on mesoporous silica nanoparticles coated with temperature sensitive gatekeeper [J].
Cho, In-Hye ;
Shim, Man Kyu ;
Jung, Bom ;
Jang, Eun Hyang ;
Park, Min-Ju ;
Kang, Han Chang ;
Kim, Jong-Ho .
MICROPOROUS AND MESOPOROUS MATERIALS, 2017, 253 :96-101
[45]   Construction of polymer coated core-shell magnetic mesoporous silica nanoparticles with triple responsive drug delivery [J].
Hegazy, Mohammad ;
Zhou, Pei ;
Wu, Guangyu ;
Wang, Lei ;
Rahoui, Nahla ;
Taloub, Nadia ;
Huang, Xin ;
Huang, Yudong .
POLYMER CHEMISTRY, 2017, 8 (38) :5852-5864
[46]   Theranostic mesoporous silica nanoparticles made of multi-nuclear gold or carbon quantum dots particles serving as pH responsive drug delivery system [J].
Akbarian, Mohsen ;
Gholinejad, Mohammad ;
Mohammadi-Samani, Soliman ;
Farjadian, Fatemeh .
MICROPOROUS AND MESOPOROUS MATERIALS, 2022, 329
[47]   Facile synthesis by a covalent binding reaction for pH-responsive drug release of carboxylated chitosan coated hollow mesoporous silica nanoparticles [J].
Liu, Qiang ;
Wang, Jiao ;
Yang, Linnan ;
Xia, Xiaofei ;
Wang, Mei ;
Chen, Shengguang ;
Zhu, Rongrong ;
Wang, Qingxiu ;
Wu, Xianzheng ;
Wang, Shilong .
IET NANOBIOTECHNOLOGY, 2018, 12 (04) :446-452
[48]   Polymer-Coated Hollow Mesoporous Silica Nanoparticles for Triple-Responsive Drug Delivery [J].
Zhang, Yuanyuan ;
Ang, Chung Yen ;
Li, Menghuan ;
Tan, Si Yu ;
Qu, Qiuyu ;
Luo, Zhong ;
Zhao, Yanli .
ACS APPLIED MATERIALS & INTERFACES, 2015, 7 (32) :18179-18187
[49]   Enzyme responsive drug delivery system based on mesoporous silica nanoparticles for tumor therapy in vivo [J].
Liu, Yun ;
Ding, Xingwei ;
Li, Jinghua ;
Luo, Zhong ;
Hu, Yan ;
Liu, Junjie ;
Dai, Liangliang ;
Zhou, Jun ;
Hou, Changjun ;
Cai, Kaiyong .
NANOTECHNOLOGY, 2015, 26 (14)
[50]   Ultrasound-Responsive Smart Drug Delivery System of Lipid Coated Mesoporous Silica Nanoparticles [J].
Amin, Muhammad Umair ;
Ali, Sajid ;
Tariq, Imran ;
Ali, Muhammad Yasir ;
Pinnapreddy, Shashank Reddy ;
Preis, Eduard ;
Woelk, Christian ;
Harvey, Richard D. ;
Hause, Gerd ;
Bruessler, Jana ;
Bakowsky, Udo .
PHARMACEUTICS, 2021, 13 (09)
12345