Completing the Arc: Targeted Inhibition of RET in Medullary Thyroid Cancer

被引：17

作者：

Houvras, Yariv ^{[1
,2
]}

机构：

[1] Weill Cornell Med Coll, New York, NY USA

[2] New York Presbyterian Hosp, New York, NY USA

来源：

JOURNAL OF CLINICAL ONCOLOGY | 2012年 / 30卷 / 02期

关键词：

MUTATIONS; CARCINOMAS; VANDETANIB; GENETICS; DISEASE; ZD6474;

D O I：

10.1200/JCO.2011.38.7639

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：200 / 202

页数：3

共 17 条

[1] Hirschsprung disease, associated syndromes and genetics: a review [J].

Amiel, J. ;

Sproat-Emison, E. ;

Garcia-Barcelo, M. ;

Lantieri, F. ;

Burzynski, G. ;

Borrego, S. ;

Pelet, A. ;

Arnold, S. ;

Miao, X. ;

Griseri, P. ;

Brooks, A. S. ;

Antinolo, G. ;

de Pontual, L. ;

Clement-Ziza, M. ;

Munnich, A. ;

Kashuk, C. ;

West, K. ;

Wong, K. K-Y ;

Lyonnet, S. ;

Chakravarti, A. ;

Tam, P. K-H ;

Ceccherini, I. ;

Hofstra, R. M. W. ;

Fernandez, R. .

JOURNAL OF MEDICAL GENETICS, 2008, 45 (01) :1-14

[2]

AstraZeneca, 2010, VAND VD6474 TABL ONC

[3]

Carlomagno F, 2002, CANCER RES, V62, P7284

[4] Disease associated mutations at valine 804 in the RET receptor tyrosine kinase confer resistance to selective kinase inhibitors [J].

Carlomagno, F ;

Guida, T ;

Anaganti, S ;

Vecchio, G ;

Fusco, A ;

Ryan, AJ ;

Billaud, M ;

Santoro, M .

ONCOGENE, 2004, 23 (36) :6056-6063

[5] Identification of tyrosine 806 as a molecular determinant of RET kinase sensitivity to ZD6474 [J].

Carlomagno, Francesca ;

Guida, Teresa ;

Anaganti, Suresh ;

Provitera, Livia ;

Kjaer, Svend ;

McDonald, Neil Q. ;

Ryan, Anderson J. ;

Santoro, Massimo .

[6] Minireview: RET/PTC rearrangements and BRAF mutations in thyroid tumorigenesis [J].

Ciampi, Raffaele ;

Nikiforov, Yuri E. .

ENDOCRINOLOGY, 2007, 148 (03) :936-941

[7] MUTATIONS IN THE RET PROTOONCOGENE ARE ASSOCIATED WITH MEN 2A AND FMTC [J].

DONISKELLER, H ;

DOU, SS ;

CHI, D ;

CARLSON, KM ;

TOSHIMA, K ;

LAIRMORE, TC ;

HOWE, JR ;

MOLEY, JF ;

GOODFELLOW, P ;

WELLS, SA .

HUMAN MOLECULAR GENETICS, 1993, 2 (07) :851-856

[8] Medullary Thyroid Cancer: Management Guidelines of the American Thyroid Association [J].

Kloos, Richard T. ;

Eng, Charis ;

Evans, Douglas B. ;

Francis, Gary L. ;

Gagel, Robert F. ;

Gharib, Hossein ;

Moley, Jeffrey F. ;

Pacini, Furio ;

Ringel, Matthew D. ;

Schlumberger, Martin ;

Wells, Samuel A., Jr. .

THYROID, 2009, 19 (06) :565-612

[9] Structure and chemical inhibition of the RET tyrosine kinase domain [J].

Knowles, Phillip P. ;

Murray-Rust, Judith ;

Kjaer, Svend ;

Scott, Rizaldy P. ;

Hanrahan, Sarah ;

Santoro, Massimo ;

Ibanez, Carlos F. ;

McDonald, Neil Q. .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (44) :33577-33587

[10] Correlation of RET somatic mutations with clinicopathological features in sporadic medullary thyroid carcinomas [J].

Moura, M. M. ;

Cavaco, B. M. ;

Pinto, A. E. ;

Domingues, R. ;

Santos, J. R. ;

Cid, M. O. ;

Bugalho, M. J. ;

Leite, V. .

BRITISH JOURNAL OF CANCER, 2009, 100 (11) :1777-1783

← 1 2 →