Carboxamides combining favorable olfactory properties with insect repellency

被引：12

作者：

Gaudin, Jean-Marc ^{[1
]}

Lander, Thierry ^{[1
]}

Nikolaenko, Olga ^{[1
]}

机构：

[1] Firmenich Co, Corp R&D Div, CH-1211 Geneva, Switzerland

来源：

CHEMISTRY & BIODIVERSITY | 2008年 / 5卷 / 04期

关键词：

D O I：

10.1002/cbdv.200890058

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

By a simple methodology, we have synthesized 68 carboxamides, with structural analogy to the most efficient mosquitoes repellent DEET (N,N-diethyl-m-toluamide, 9). Eight of them have very promising olfactory profiles. In addition, 34 carboxamides have been tested for their repellency properties against three breeds of cockroach; six of them are excellent in this domain. Two of these, the 2-ethyl-N-isopropyl-N-methylbutanamide and N,N-diallyl-2-ethylbutanamide combine both the positive aspects, and are thus very good candidates for use in functional perfumery, and more particularly in home-care formulations.

引用

页码：617 / 635

页数：19

共 21 条

[1]

BEHAN JM, 1998, Patent No. 0019822

[2]

BIRCH G, 2000, LFRA INGREDIENTS HDB

[3]

Boelens M., 2003, Perfumer & Flavorist, V28, P18

[4] EFFECT OF CARBONYL SUBSTITUENTS ON THE BARRIER TO ROTATION IN N-ETHYL-N-METHYLAMIDES [J].

BONACORSO, HG ;

CARO, MSB ;

ZANATTA, N ;

MARTINS, MAP .

MAGNETIC RESONANCE IN CHEMISTRY, 1993, 31 (05) :451-454

[5]

BREANT C, 1979, Patent No. 0017604

[6]

Dev S., 1997, INSECTICIDES NATURAL

[7]

Erman M., 2004, Perfumer & Flavorist, V29, P36

[8]

Erman M., 2002, Perfumer & Flavorist, V27, P32

[9]

Galopin CC, 2004, ACS SYM SER, V867, P139

[10]

GORDON DG, 1969, COMPLEAT COCKROACH C

← 1 2 3 →