Cutaneous Epithelioid Hemangioendothelioma on the Sole of a Child

被引:15
作者
Carranza-Romero, Carmen [1 ]
Maria Molina-Ruiz, Ana [1 ]
Perna Monroy, Cristian [2 ]
Cuevas Santos, Jesus [2 ]
Requena, Luis [1 ]
机构
[1] Univ Autonoma Madrid, Fdn Jimenez Diaz, Dept Dermatol, Madrid, Spain
[2] Univ Alcala de Henares, Hosp Univ Guadalajara, Dept Pathol, Madrid, Spain
关键词
TRANSCRIPTION FACTOR; ORAL-CAVITY; SOFT-TISSUE; SKIN; EXPRESSION; CARCINOMA; MARKER; TUMORS;
D O I
10.1111/pde.12539
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Epithelioid hemangioendothelioma (EHE) has been considered to be a low-grade malignant vascular neoplasm, although follow-up of recent series has demonstrated that EHE involving the skin and soft tissues should be better regarded as a fully malignant vascular tumor since it has more metastatic potential than previously thought. We report a case of an EHE involving the left sole of 6-year-old boy, the youngest patient with cutaneous EHE described to date. Immunohistochemical studies demonstrated a lymphatic endothelial line of differentiation for neoplastic cells. Cutaneous EHE is rare in childhood, with only five previously described cases.
引用
收藏
页码:E64 / E69
页数:6
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