Differential Setup of Light-Addressable Potentiometric Sensor with an Enzyme Reactor in a Flow Channel

被引：12

作者：

Miyamoto, Ko-ichiro ^{[1
]}

Yoshida, Midori ^{[1
]}

Sakai, Taito ^{[1
]}

Matsuzaka, Atsushi ^{[1
]}

Wagner, Torsten ^{[1
]}

Kanoh, Shin'ichiro ^{[2
]}

Yoshinobu, Tatsuo ^{[1
]}

Schoening, Michael J. ^{[3
,4
]}

机构：

[1] Tohoku Univ, Sendai, Miyagi 9808579, Japan

[2] Tohoku Inst Technol, Sendai, Miyagi 9828577, Japan

[3] Aachen Univ Appl Sci, D-52428 Julich, Germany

[4] Res Ctr Julich, D-52425 Julich, Germany

来源：

JAPANESE JOURNAL OF APPLIED PHYSICS | 2011年 / 50卷 / 04期

基金：

日本学术振兴会;

关键词：

PH-IMAGING SENSOR; INJECTION ANALYSIS; THROUGH CELL; RESOLUTION; POTASSIUM; BIOSENSOR; CALCIUM; LAPS; IONS; CHIP;

D O I：

10.1143/JJAP.50.04DL08

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

The light-addressable potentiometric sensor (LAPS) was combined with an enzyme reactor in a fluidic channel. The fluidic channel was mounted on the sensor plate and the enzyme reactor was connected to the fluidic channel. The enzyme reactor was filled with glass beads as enzyme carrier modified by urease which catalyzed production of ammonia depending on the concentration of urea. Double-channel LAPS measurement was performed at the both side of upper and lower stream of the enzyme reactor which realized a differential measurement and eliminated the drift component of the measurement. (C) 2011 The Japan Society of Applied Physics

引用

页数：5

共 26 条

[1] DEVELOPMENT OF AN ION-SENSITIVE SOLID-STATE DEVICE FOR NEUROPHYSIOLOGICAL MEASUREMENTS
BERGVELD, P
[J]. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1970, BM17 (01) : 70 - &
[2] Recent developments in urea biosensors
Dhawan, Gunjan
Sumana, Gajjala
Malhotra, B. D.
[J]. BIOCHEMICAL ENGINEERING JOURNAL, 2009, 44 (01) : 42 - 52
[3] Photocurable membranes for ion-selective light-addressable potentiometric sensor
Ermolenko, Y
Yoshinobu, T
Mourzina, Y
Levichev, S
Furuichi, K
Vlasov, Y
Schöning, MJ
Iwasaki, H
[J]. SENSORS AND ACTUATORS B-CHEMICAL, 2002, 85 (1-2) : 79 - 85
[4] LIGHT-ADDRESSABLE POTENTIOMETRIC SENSOR FOR BIOCHEMICAL SYSTEMS
HAFEMAN, DG
PARCE, JW
MCCONNELL, HM
[J]. SCIENCE, 1988, 240 (4856) : 1182 - 1185
[5] ION-SENSING DEVICES WITH SILICON-NITRIDE AND BOROSILICATE GLASS INSULATORS
HARAME, DL
BOUSSE, LJ
SHOTT, JD
MEINDL, JD
[J]. IEEE TRANSACTIONS ON ELECTRON DEVICES, 1987, 34 (08) : 1700 - 1707
[6] In situ study of DNA attachment and hybridization at silicon surfaces by infrared absorption spectroscopy
Ishibashi, Ken-ichi
Tanaka, Kohki
Hirano-Iwata, Ayumi
Miyamoto, Ko-ichiro
Kimura, Yasuo
Niwano, Michio
[J]. JAPANESE JOURNAL OF APPLIED PHYSICS, 2008, 47 (04) : 3204 - 3208
[7] Chemical amplification: Continuous-flow PCR on a chip
Kopp, MU
de Mello, AJ
Manz, A
[J]. SCIENCE, 1998, 280 (5366) : 1046 - 1048
[8] INTEGRATED FIELD-EFFECT ELECTRODE FOR BIOPOTENTIAL RECORDING
MATSUO, T
WISE, KD
[J]. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1974, BM21 (06) : 485 - 487
[9] Chemical image scanner based on FDM-LAPS
Miyamoto, K.
Kuwabara, Yohei
Kanoh, Shin'ichiro
Yoshinobu, Tatsuo
Wagner, Torsten
Schoening, Michael J.
[J]. SENSORS AND ACTUATORS B-CHEMICAL, 2009, 137 (02) : 533 - 538
[10] IMPROVEMENT OF SPATIAL-RESOLUTION OF A LASER-SCANNING PH-IMAGING SENSOR
NAKAO, M
YOSHINOBU, T
IWASAKI, H
[J]. JAPANESE JOURNAL OF APPLIED PHYSICS PART 2-LETTERS, 1994, 33 (3A): : L394 - L397

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