Epigenetic Modification of Redox Regulation in Breast Cancer

被引：0

作者：

Gou Xiao-Meng ^{[1
]}

Sun Hong-Liang ^{[1
]}

Zhang Zhong-Guo ^{[1
]}

Xue Xin-Yu ^{[1
]}

Hao Jing-Zhi ^{[1
]}

Zhang Hong-Sheng ^{[1
]}

机构：

[1] Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China

来源：

PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS | 2018年 / 45卷 / 12期

关键词：

epigenetic modification; reactive oxygen species(ROS); redox state; breast cancer; MANGANESE SUPEROXIDE-DISMUTASE; HYDROGEN-PEROXIDE; METHYLATION; EXPRESSION; OXIDASES; ROLES; CELLS; NRF2; ROS;

D O I：

10.16476/j.pibb.2018.0144

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Breast cancer is one of the most important malignant tumors affecting women's health. Epigenetic modification and oxidative stress caused by excessive accumulation of reactive oxygen species (ROS) play a key role in the occurrence and development of breast cancer. In addition, epigenetic modification and the production and clearance of ROS interact with each other. In this paper, epigenetic modification and ROS involved in the occurrence and development of breast cancer are reviewed in order to provide possible ideas for seeking biomarkers and precise therapy for the treatment of breast cancer.

引用

页码：1224 / 1231

页数：8

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