Treatment of psoriasis with etanercept in immunocompromised patients: Two case reports

被引：18
作者：
De Simone, Clara [1 ]
Perino, Francesca [1 ]
Caldarola, Giacomo [1 ]
D'Agostino, Magda [1 ]
Peris, Ketty [1 ]
机构：
[1] Univ Cattolica Sacro Cuore, Dept Dermatol, Rome, Italy
来源：
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 2016年 / 44卷
关键词：
Antitumour necrosis factor- agents; comorbidities; etanercept; psoriasis; psoriatic arthritis; HUMAN-IMMUNODEFICIENCY-VIRUS; LIVER-TRANSPLANT; HIV; THERAPY; PATHOGENESIS; ARTHRITIS;
D O I：
10.1177/0300060515593250
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Tumour necrosis factor (TNF)- blocking agents have revolutionized the treatment of psoriasis and psoriatic arthritis. Concerns remain about increased susceptibility to infection and onset of malignancies, and the use of TNF- agents in patients with HIV infection or undergoing immunosuppressant treatment is debated. We report cases of severe plaque psoriasis in a patient with HIV infection and in a liver transplant recipient who were successfully treated with etanercept, an anti-TNF- agent, without notable side-effects.
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页码：67 / 71
页数：5
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