Synthesis of Chiral Selenazolines from N-Acyloxazolidinones via a Selenative Rearrangement of Chiral Cyclic Skeletons

被引：22

作者：

Shibahara, Fumitoshi ^{[1
]}

Fukunaga, Tomoki ^{[1
]}

Kubota, Saki ^{[1
]}

Yoshida, Akihito ^{[1
]}

Murai, Toshiaki ^{[1
]}

机构：

[1] Gifu Univ, Fac Engn, Dept Chem & Biomol Sci, Gifu 5011193, Japan

来源：

ORGANIC LETTERS | 2018年 / 20卷 / 18期

关键词：

THIAZOLINE LIGANDS; NATURAL-PRODUCTS; SELENIUM; OXAZOLINES; SULFUR;

D O I：

10.1021/acs.orglett.8b02520

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A synthetic route to chiral selenazolines from readily available N-acyloxazolidinones via a selenative rearrangement of a chiral cyclic skeleton is reported. The reaction proceeds in the presence of elemental selenium, a hydrochlorosilane, and an amine. Although the stability of the obtained selenazoline products is relatively low, a wide range of selenazolines was successfully prepared.

引用

页码：5826 / 5830

页数：5

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