BIMEKIZUMAB IN PATIENTS WITH ACTIVE NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS: 24-WEEK EFFICACY & SAFETY FROM BE MOBILE 1, A PHASE 3, MULTICENTRE, RANDOMISED, PLACEBO-CONTROLLED STUDY

被引：12

作者：

Deodhar, A. ^{[1
]}

Van der Heijde, D. ^{[2
]}

Gensler, L. S. ^{[3
]}

Xu, H. ^{[4
]}

Gaffney, K. ^{[5
]}

Dobashi, H. ^{[6
]}

Maksymowych, W. P. ^{[7
]}

Rudwaleit, M. ^{[8
]}

Magrey, M. ^{[9
]}

Elewaut, D. ^{[10
,11
]}

Oortgiesen, M. ^{[12
]}

Fleurinck, C. ^{[13
]}

Ellis, A. ^{[12
]}

Vaux, T. ^{[14
]}

Smith, J. ^{[14
]}

Baraliakos, X. ^{[15
]}

机构：

[1] Oregon Hlth & Sci Univ, Div Arthrit & Rheumat Dis, Portland, OR 97201 USA

[2] Leiden Univ Med Ctr, Dept Rheumatol, Leiden, Netherlands

[3] Univ Calif San Francisco, Dept Rheumatol, San Francisco, CA 94143 USA

[4] Second Mil Med Univ, Shanghai Changzheng Hosp, Dept Rheumatol & Immunol, Shanghai, Peoples R China

[5] Norfolk & Norwich Univ Hosp NHS Trust, Dept Rheumatol, Norwich, Norfolk, England

[6] Kagawa Univ, Div Hematol Rheumatol & Resp Med, Dept Internal Med, Fac Med, Takamatsu, Kagawa, Japan

[7] Univ Alberta, Dept Med, Edmonton, AB, Canada

[8] Univ Bielefeld, Klinikum Bielefeld, Bielefeld, Germany

[9] Case Western Reserve Univ, Metrohlth Med Ctr, Cleveland, OH USA

[10] Ghent Univ Hosp, Dept Rheumatol, Ghent, Belgium

[11] Univ Ghent, Ctr Inflammat Res, Ghent, Belgium

[12] UCB Pharma, Raleigh, NC USA

[13] UCB Pharma, Brussels, Belgium

[14] UCB Pharma, Slough, Berks, England

[15] Ruhr Univ Bochum, Rheumazentrum Ruhrgebiet Herne, Bochum, Germany

来源：

ANNALS OF THE RHEUMATIC DISEASES | 2022年 / 81卷

关键词：

D O I：

10.1136/annrheumdis-2022-eular.2416

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

POS0939

引用

页码：772 / 773

页数：2

共 2 条

[1]

Gensler L, 2021, ARTHRITIS RHEUMATOL, V73, P1015

[2] Dual neutralisation of interleukin-17A and interleukin-17F with bimekizumab in patients with active ankylosing spondylitis: results from a 48-week phase IIb, randomised, double-blind, placebo-controlled, dose-ranging study [J].

van der Heijde, Desiree ;

Gensler, Lianne S. ;

Deodhar, Atul ;

Baraliakos, Xenofon ;

Poddubnyy, Denis ;

Kivitz, Alan ;

Farmer, Mary Katherine ;

Baeten, Dominique ;

Goldammer, Nadine ;

Coarse, Jason ;

Oortgiesen, Marga ;

Dougados, Maxime .

ANNALS OF THE RHEUMATIC DISEASES, 2020, 79 (05) :595-604

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