Computer aided morphometric analysis of oral leukoplakia and oral squamous cell carcinoma

被引：4
|
作者：
Gupta, K. [1 ]
Gupta, J. [2 ]
Miglani, R. [3 ]
机构：
[1] Mithila Minor Dent Coll & Hosp, Dept Oral & Maxillofacial Pathol, Darbhanga 846002, Bihar, India
[2] Mithila Minor Dent Coll & Hosp, Dept Oral Med & Radiol, Darbhanga, Bihar, India
[3] Mithila Minor Dent Coll & Hosp, Endodont, Darbhanga, Bihar, India
来源：
BIOTECHNIC & HISTOCHEMISTRY | 2016年 / 91卷 / 04期
关键词：
image analysis; leukoplakia; morphometry; oral squamous cell carcinoma; OSCC;
D O I：
10.3109/10520295.2016.1139181
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
We compared the changes in the cells in the basal layer of normal mucosa, oral leukoplakia with dysplasia and different grades of oral squamous cell carcinoma (OSCC) using computer aided image analysis of tissue sections. We investigated three morphometric parameters: nuclear area (NA), cell area (CA) and their ratio (NA:CA). NA and NA:CA ratio showed a statistically significant increase from dysplasia to increasing grades of OSCC. Nuclear size was useful for differentiating normal tissue, potentially malignant leukoplakia and OSCC.
引用
收藏
页码：251 / 254
页数：4
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