Substrate-Controlled Selectivity Switch in a Three-Component Reaction: A Ag-Catalyzed Strategy for the Synthesis of Functionalized Imidazoles

被引：27

作者：

Wang, Changcheng ^{[1
]}

Wang, Enming ^{[1
]}

Chen, Weixin ^{[1
]}

Zhang, Lijuan ^{[1
]}

Zhan, Haiying ^{[1
]}

Wu, Yuanheng ^{[1
]}

Cao, Hua ^{[1
]}

机构：

[1] Guangdong Pharmaceut Univ, Sch Chem & Chem Engn, Zhongshan 528458, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 82卷 / 17期

基金：

中国国家自然科学基金;

关键词：

HIGHLY SUBSTITUTED IMIDAZOLES; C-H BONDS; REGIOSELECTIVE SYNTHESIS; ONE-POT; METAL-FREE; MULTICOMPONENT SYNTHESIS; DIRECT ARYLATION; METHYL KETONES; DERIVATIVES; ALKYNES;

D O I：

10.1021/acs.joc.7b01781

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient Ag-catalyzed three-component reaction of amidines, ynals, and alcohols, phenols, or water has been developed. This strategy provides a wide range of substrates and represents a simple process for the preparation of different imidazole derivatives in good yields with high regioselectivities.

引用

页码：9144 / 9153

页数：10

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