2-Arylbenzofuran, Flavonoid, and Tyrosinase Inhibitory Constituents of Morus yunnanensis

被引：67
作者：
Hu, Xiao [1 ]
Wu, Jin-Wei [2 ]
Wang, Meng [1 ]
Yu, Mei-Hua [1 ]
Zhao, Qin-Shi [3 ]
Wang, He-Yao [2 ]
Hou, Ai-Jun [1 ]
机构：
[1] Fudan Univ, Sch Pharm, Dept Pharmacognosy, Shanghai 201203, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
[3] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
来源：
JOURNAL OF NATURAL PRODUCTS | 2012年 / 75卷 / 01期
基金：
中国国家自然科学基金;
关键词：
KOJIC ACID; ALBA L; LEAVES; PLANTS; BLOOD;
D O I：
10.1021/np2007318
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two novel 2-arylbenzofuran dimers, morusyunnansins A and B (1 and 2), two new biflavonoids, morusyunnansins C and D (3 and 4), two new flavans, morusyunnansins E and F (5 and 6), and four known flavans (7-10) were isolated from the leaves of Morus yunnanensis. Compounds 5-8 showed potent inhibitory effects on mushroom tyrosinase with IC50 values ranging from 0.12 +/- 0.02 to 1.43 +/- 0.43 mu M.
引用
收藏
页码：82 / 87
页数：6
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