2-Arylbenzofuran, Flavonoid, and Tyrosinase Inhibitory Constituents of Morus yunnanensis

被引：67

作者：

Hu, Xiao ^{[1
]}

Wu, Jin-Wei ^{[2
]}

Wang, Meng ^{[1
]}

Yu, Mei-Hua ^{[1
]}

Zhao, Qin-Shi ^{[3
]}

Wang, He-Yao ^{[2
]}

Hou, Ai-Jun ^{[1
]}

机构：

[1] Fudan Univ, Sch Pharm, Dept Pharmacognosy, Shanghai 201203, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China

[3] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China

来源：

JOURNAL OF NATURAL PRODUCTS | 2012年 / 75卷 / 01期

基金：

中国国家自然科学基金;

关键词：

KOJIC ACID; ALBA L; LEAVES; PLANTS; BLOOD;

D O I：

10.1021/np2007318

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two novel 2-arylbenzofuran dimers, morusyunnansins A and B (1 and 2), two new biflavonoids, morusyunnansins C and D (3 and 4), two new flavans, morusyunnansins E and F (5 and 6), and four known flavans (7-10) were isolated from the leaves of Morus yunnanensis. Compounds 5-8 showed potent inhibitory effects on mushroom tyrosinase with IC50 values ranging from 0.12 +/- 0.02 to 1.43 +/- 0.43 mu M.

引用

页码：82 / 87

页数：6

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