Highly fluorinated surfactants in liposome technology

被引：9

作者：

Szonyi, S

Watzke, HJ

Cambon, A

机构：

[1] NESTLE LTD, CENT RES, LAUSANNE, SWITZERLAND

[2] UNIV NICE, LAB CHIM ORGAN FLUOR, F-06108 NICE 02, FRANCE

来源：

THIN SOLID FILMS | 1996年 / 284卷

关键词：

fluorine; liposome; self-assembly; surfactant;

D O I：

10.1016/S0040-6090(95)08442-8

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The stability of liposomes was found to be considerably improved by the incorporation of perfluoroalkylated lipids. Therefore we have developed an easy synthesis procedure to obtain vesicle-forming perfluoroalkylated double-chain surfactants for liposome technology applications. This paper describes new fluorine-containing liposomes obtained by sonication of highly fluorinated mixed-chain surfactants and by gentle mixing of perfluoroalkylated cationic and anionic single-chain surfactants. The observation of liposomes by electron microscopy reveals the existence of unilamellar polydispersed aggregates whose mean sizes were measured by quasi-elastic light scattering.

引用

页码：769 / 771

页数：3

共 15 条

[1] LIPOSOMES FROM ALPHA,OMEGA-DIPOLAR AMPHIPHILES WITH A POLYMERIZABLE DIENE MOIETY IN THE HYDROPHOBIC CHAIN [J].