Epidemiology of Antiphospholipid Syndrome in the General Population

被引：107

作者：

Dabit, Jesse Y. ^{[1
]}

Valenzuela-Almada, Maria O. ^{[1
]}

Vallejo-Ramos, Sebastian ^{[1
]}

Duarte-Garcia, Ali ^{[1
,2
]}

机构：

[1] Mayo Clin, Div Rheumatol, Rochester, MN 55905 USA

[2] Mayo Clin, Robert D & Patricia E Kern Ctr Sci Hlth Care Deli, 200 First St SW, Rochester, MN 55905 USA

来源：

CURRENT RHEUMATOLOGY REPORTS | 2021年 / 23卷 / 12期

关键词：

Antiphospholipid syndrome; Epidemiology; SYSTEMIC-LUPUS-ERYTHEMATOSUS; GLYCOPROTEIN-I ANTIBODIES; ANTICARDIOLIPIN ANTIBODIES; MYOCARDIAL-INFARCTION; PREVALENCE; RISK; CLASSIFICATION; AUTOANTIBODIES; MORBIDITY; MORTALITY;

D O I：

10.1007/s11926-021-01038-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose of Review The epidemiology of antiphospholipid syndrome (APS) is poorly understood. Here, we review the current understanding of the epidemiology of antiphospholipid syndrome in the general population and the frequency of antiphospholipid antibodies in the general population in patients with obstetric morbidity, arterial events, and venous thromboembolism. Recent Findings There have been few population-based studies that estimated the prevalence and incidence of APS. The estimated incidence and prevalence among most these studies ranged between 1 and 2 cases per 100,000 and 40 and 50 cases per 100,000 respectively. The prevalence of antiphospholipid antibodies in patients with obstetric morbidity was 6-9%, while in arterial events and venous thromboembolism is 9-10%. However, this data remains limited. Mortality of patients with APS is 50-80% higher than the general population. The epidemiology of APS has been difficult to elucidate. Population-based studies patients with diverse age, racial, and ethnic backgrounds are needed.

引用

页数：9

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