Frequency-Dependent Cortical Interactions during Semantic Processing: An Electrocorticogram Cross-spectrum Analysis Using a Semantic Space Model

被引：5

作者：

Sato, Naoyuki ^{[1
]}

Matsumoto, Riki ^{[2
,3
]}

Shimotake, Akihiro ^{[3
,4
]}

Matsuhashi, Masao ^{[4
,5
]}

Otani, Mayumi ^{[3
]}

Kikuchi, Takayuki ^{[6
]}

Kunieda, Takeharu ^{[6
,7
]}

Mizuhara, Hiroaki ^{[8
]}

Miyamoto, Susumu ^{[6
]}

Takahashi, Ryosuke ^{[3
]}

Ikeda, Akio ^{[4
]}

机构：

[1] Future Univ Hakodate, Sch Syst Informat Sci, Dept Complex & Intelligent Syst, Hakodate, Hokkaido 0418655, Japan

[2] Kobe Univ, Div Neurol, Grad Sch Med, Kobe, Hyogo 6500017, Japan

[3] Kyoto Univ, Kyoto Univ Hosp, Dept Neurol, Grad Sch Med,Sakyo Ku, Kyoto 6068507, Japan

[4] Kyoto Univ, Dept Epilepsy Movement Disorders & Physiol, Grad Sch Med, Sakyo Ku, Kyoto 6068507, Japan

[5] Kyoto Univ, Human Brain Res Ctr, Grad Sch Med, Kyoto 6068507, Japan

[6] Kyoto Univ, Kyoto Univ Hosp, Dept Neurosurg, Grad Sch Med,Sakyo Ku, Kyoto 6068507, Japan

[7] Ehime Univ, Dept Neurosurg, Grad Sch Med, Shizukawa Toon City, Ehime 7910295, Japan

[8] Kyoto Univ, Grad Sch Informat, Sakyo Ku, Kyoto 6068501, Japan

来源：

CEREBRAL CORTEX | 2021年 / 31卷 / 09期

基金：

日本学术振兴会;

关键词：

anterior temporal lobe; distributed semantic coding; electrocorticogram; language; semantic memory; ANTERIOR TEMPORAL-LOBE; REPRESENTATION; OSCILLATIONS; OBJECT; MEMORY; ACQUISITION; SIGNALS; NORMS; SET;

D O I：

10.1093/cercor/bhab089

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Convergent evidence has demonstrated that semantics are represented by the interaction between a multimodal semantic hub at the anterior temporal lobe (ATL) and other modality-specific association cortical areas. Electrocorticogram (ECoG) recording with high spatiotemporal resolutions is efficient in evaluating such cortical interactions; however, this has not been a focus of preceding studies. The present study evaluated cortical interactions during picture naming using a novel ECoG cross-spectrum analysis, which was formulated from a computational simulation of neuronal networks and combined with a vector space model of semantics. The results clarified three types of frequency-dependent cortical networks: 1) an earlier-period (0.2-0.8 s from stimulus onset) high-gamma-band (90-150 Hz) network with a hub at the posterior fusiform gyrus, 2) a later-period (0.4-1.0 s) beta-band (15-40 Hz) network with multiple hubs at the ventral ATL and posterior middle temporal gyrus, and 3) a pre-articulation theta-band (4-7 Hz) network distributed over widely located cortical regions. These results suggest that frequency-dependent cortical interactions can characterize the underlying processes of semantic cognition, and the beta-band network with a hub at the ventral ATL is especially associated with the formation of semantic representation.

引用

页码：4329 / 4339

页数：11