The Cretan Aging Cohort: Cohort Description and Burden of Dementia and Mild Cognitive Impairment

被引：23

作者：

Zaganas, Ioannis V. ^{[1
]}

Simos, Panagiotis ^{[2
,3
]}

Basta, Maria ^{[2
]}

Kapetanaki, Stefania ^{[1
]}

Panagiotakis, Symeon ^{[4
]}

Koutentaki, Irini ^{[2
]}

Fountoulakis, Nikolaos ^{[4
]}

Bertsias, Antonios ^{[5
]}

Duijker, George ^{[5
]}

Tziraki, Chariklia ^{[6
]}

Scarmeas, Nikolaos ^{[7
]}

Plaitakis, Andreas ^{[8
]}

Boumpas, Dimitrios ^{[9
]}

Lionis, Christos ^{[5
]}

Vgontzas, Alexandros N. ^{[2
]}

机构：

[1] Univ Crete, Med Sch, Neurol Dept, Iraklion 71003, Crete, Greece

[2] Univ Crete, Med Sch, Psychiat Dept, Iraklion, Crete, Greece

[3] Fdn Res & Technol, Inst Comp Sci, Iraklion, Greece

[4] Univ Crete, Med Sch, Internal Med Dept, Iraklion, Crete, Greece

[5] Univ Crete, Med Sch, Clin Social & Family Med, Iraklion, Crete, Greece

[6] Community Elders Club, Res Dept, Jerusalem, Israel

[7] Univ Athens, Dept Social Med Psychiat & Neurol, Neurol Clin 1, Aiginit Hosp, Athens, Greece

[8] Mt Sinai Sch Med, Neurol Dept, New York, NY USA

[9] Univ Athens, Med Sch, Internal Med Dept, Athens, Greece

来源：

AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS | 2019年 / 34卷 / 01期

关键词：

dementia; education and dementia; mild cognitive impairment; dementia burden; CARDIOVASCULAR RISK-FACTORS; DIAGNOSTIC-CRITERIA; ALZHEIMERS-DISEASE; GENERAL-PRACTICE; FOLLOW-UP; PREVALENCE; EDUCATION; POPULATION; DECLINE; EUROPE;

D O I：

10.1177/1533317518802414

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Our aim was to explore the burden of dementia in the Cretan Aging Cohort, comprised of 3140 persons aged >= 60 years (56.8% women, 5.8 +/- 3.3 years formal education, 86.2% living in rural areas) who attended selected primary health-care facilities on the island of Crete, Greece. In the first study phase, a formal diagnosis of dementia had been reached in 4.0% of the participants. However, when selected 505 participants underwent thorough neuropsychiatric evaluation in the second phase of this study (344 with Mini-Mental State Examination [MMSE] <24 and 161 with MMSE >= 24), and results were extrapolated to the entire cohort, the prevalence of dementia and mild cognitive impairment was estimated at 10.8% (9.7%-11.9%) and 32.4% (30.8%-34.0%), respectively. Using both the field diagnostic data and the extrapolated data, the highest dementia prevalence (27.2%) was found in the 80- to 84-year-old group, who also showed the lowest educational level, apparently due to lack of schooling during World War II.

引用

页码：23 / 33

页数：11

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