Polymer Pen Lithography (PPL)-Induced Site-Specific Click Chemistry for the Formation of Functional Glycan Arrays

被引:44
作者
Bian, Shudan [1 ,2 ]
He, Jiajun [3 ]
Schesing, Kevin B. [1 ,2 ]
Braunschweig, Adam B. [1 ,2 ]
机构
[1] NYU, Dept Chem, New York, NY 10003 USA
[2] NYU, Inst Mol Design, New York, NY 10003 USA
[3] Stanford Univ, Dept Energy Resources Engn, Stanford, CA 94305 USA
基金
美国国家科学基金会;
关键词
arrays; carbohydrates; dip-pen nanolithography; click chemistry; NANOLITHOGRAPHY; MECHANISMS; BIOCHIPS; FEATURES; PLATFORM; FORCE; TOOLS; GOLD; SIZE;
D O I
10.1002/smll.201102707
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Polymer pen lithography (PPL) can be combined with the Cu I-catalyzed azide-alkyne click reaction to create molecular arrays with control over orientation and sub-1 μm feature sizes over cm2 areas. The process has been applied to the deposition of carbohydrates to form functional glycochips. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:2000 / 2005
页数:6
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