Treatment-Related Change Versus Tumor Recurrence in High-Grade Gliomas: A Diagnostic Conundrum-Use of Dynamic Susceptibility Contrast-Enhanced (DSC) Perfusion MRI

被引：102

作者：

Fatterpekar, Girish M. ^{[1
]}

Galheigo, Diogo ^{[1
]}

Narayana, Ashwatha ^{[2
]}

Johnson, Glyn ^{[3
]}

Knopp, Edmond ^{[1
,4
]}

机构：

[1] NYU, Sch Med, NYU Langone Med Ctr, Neuroradiol Sect, New York, NY 10016 USA

[2] NYU, Sch Med, Langone Med Ctr, Dept Radiat Oncol, New York, NY 10016 USA

[3] NYU, Sch Med, Langone Med Ctr, Dept Radiol, New York, NY 10016 USA

[4] NYU, Sch Med, Langone Med Ctr, Dept Neurosurg, New York, NY 10016 USA

来源：

AMERICAN JOURNAL OF ROENTGENOLOGY | 2012年 / 198卷 / 01期

关键词：

perfusion; pseudoprogression; pseudoresponse; radiation necrosis; tumor recurrence; CEREBRAL BLOOD-VOLUME; BEVACIZUMAB PLUS IRINOTECAN; MALIGNANT GLIOMAS; BRAIN-TUMORS; GLIOBLASTOMA PATIENTS; RADIATION NECROSIS; PHASE-II; PSEUDOPROGRESSION; RADIOTHERAPY; TEMOZOLOMIDE;

D O I：

10.2214/AJR.11.7417

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

OBJECTIVE. The purpose of this article is to address radiation necrosis, pseudoprogression, and pseudoresponse relative to high-grade gliomas and evaluate the role of conventional MRI and, in particular, dynamic susceptibility contrast-enhanced perfusion MRI in assessing such treatment-related changes from tumor recurrence. CONCLUSION. Posttreatment imaging assessment of high-grade gliomas remains challenging. Familiarity with the expected MR imaging appearances of treatment-related change and tumor recurrence will help distinguish these entities allowing appropriate management.

引用

页码：19 / 26

页数：8

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