The real world cost and health resource utilization associated to manic episodes: The MANACOR study

被引:12
作者
Hidalgo-Mazzei, Diego [1 ]
Undurraga, Juan [1 ,2 ]
Reinares, Maria [1 ]
del Mar Bonnin, Caterina [1 ]
Saez, Cristina [3 ]
Mur, Maria [4 ]
Nieto, Evaristo [5 ]
Vieta, Eduard [1 ]
机构
[1] Univ Barcelona, Programa Trastornos Bipolares, Inst Neurociencias, Hosp Clin Barcelona,IDIBAPS,CIBERSAM, Barcelona, Cataluna, Spain
[2] Univ Desarrollo, Clin Alemana, Fac Med, Dept Psiquiatria, Santiago, Chile
[3] CIBERSAM, Inst Pere Mata, Hosp Psiquiatr Univ, Reus, Cataluna, Spain
[4] Univ Lleida, Serv Salud Mental, Hosp Santa Maria, Inst Invest Biomed IRB Lleida, Lleida, Cataluna, Spain
[5] Red Asistencial Univ Manresa, Althaia, Manresa, Catalonia, Spain
来源
REVISTA DE PSIQUIATRIA Y SALUD MENTAL | 2015年 / 8卷 / 02期
关键词
Bipolar disorder; Mania; Cost; Burden; BIPOLAR DISORDER; RATING-SCALE; SPECIALIZED-CARE; ECONOMIC BURDEN; CGI-BP; VALIDITY; RELIABILITY; PREVALENCE; DEPRESSION; SOCIETY;
D O I
10.1016/j.rpsm.2015.01.003
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Introduction: Bipolar disorder is a relapsing-remitting condition affecting approximately 1-2% of the population. Even when the treatments available are effective, relapses are still very frequent. Therefore, the burden and cost associated to every new episode of the disorder have relevant implications in public health. The main objective of this study was to estimate the associated health resource consumption and direct costs of manic episodes in a real world clinical setting, taking into consideration clinical variables. Methods: Bipolar I disorder patients who recently presented an acute manic episode based on DSM-IV criteria were consecutively included. Sociodemographic variables were retrospectively collected and during the 6 following months clinical variables were prospectively assessed (YMRS, HDRS-17,FAST and CGI-BP-M). The health resource consumption and associate cost were estimated based on hospitalization days, pharmacological treatment, emergency department and outpatient consultations. Results: One hundred sixty-nine patients patients from 4 different university hospitals in Catalonia (Spain) were included. The mean direct cost of the manic episodes was (sic)4,771. The 77% ((sic)3,651) was attributable to hospitalization costs while 14% ((sic)684) was related to pharmacological treatment, 8% ((sic)386) to outpatient visits and only 1% ((sic)50) to emergency room visits. The hospitalization days were the main cost driver. An initial FAST score >41 significantly predicted a higher direct cost. Conclusions: Our results show the high cost and burden associated with BD and the need to design more cost-efficient strategies in the prevention and management of manic relapses in order to avoid hospital admissions. Poor baseline functioning predicted high costs, indicating the importance of functional assessment in bipolar disorder. (C) 2014 SEP y SEPB. Published by Elsevier Espana, S.L.U. All rights reserved.
引用
收藏
页码:55 / 64
页数:10
相关论文
共 46 条
[1]  
Abdul Pari AA, 2014, BIPOLAR DISORD
[2]  
[Anonymous], 2000, DIAGN STAT MAN MENT, DOI DOI 10.1176/APPI.BOOKS.9780890425787
[3]   The lifetime cost of bipolar disorder in the US - An estimate for new cases in 1998 [J].
Begley, CE ;
Annegers, JF ;
Swann, AC ;
Lewis, C ;
Coan, S ;
Schnapp, WB ;
Bryant-Comstock, L .
PHARMACOECONOMICS, 2001, 19 (05) :483-495
[4]  
Belmaker R H, 2004, Discov Med, V4, P239
[5]   A comparative psychometric study of the Spanish versions with 6, 17, and 21 items of the Hamilton Depression Rating Scale [J].
Bobes, J ;
Bulbena, A ;
Luque, A ;
Dal-Ré, R ;
Ballesteros, J ;
Ibarra, N .
MEDICINA CLINICA, 2003, 120 (18) :693-700
[6]   The impact of repeated manic episodes and executive dysfunction on work adjustment in bipolar disorder [J].
Bonnin, C. M. ;
Torrent, C. ;
Goikolea, J. M. ;
Reinares, M. ;
Sole, B. ;
Valenti, M. ;
Sanchez-Moreno, J. ;
Hidalgo, D. ;
Tabares-Seisdedos, R. ;
Martinez-Aran, A. ;
Vieta, E. .
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, 2014, 264 (03) :247-254
[7]   The increasing burden of mental and neurological disorders [J].
Catala-Lopez, Ferran ;
Genova-Maleras, Ricard ;
Vieta, Eduard ;
Tabares-Seisdedos, Rafael .
EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2013, 23 (11) :1337-1339
[8]   Spanish version of a scale for the assessment of mania:: validity and reliability of the Young Mania Rating Scale [J].
Colom, F ;
Vieta, E ;
Martínez-Arán, A ;
Garcia-Garcia, M ;
Reinares, M ;
Torrent, C ;
Goikolea, JM ;
Banús, S ;
Salamero, M .
MEDICINA CLINICA, 2002, 119 (10) :366-371
[9]   Annual cost of bipolar disorder to UK society [J].
Das Gupta, R ;
Guest, JF .
BRITISH JOURNAL OF PSYCHIATRY, 2002, 180 :227-233
[10]   Verbal memory as a mediator in the relationship between subthreshold depressive symptoms and functional outcome in bipolar disorder [J].
del Mar Bonnin, Caterina ;
Gonzalez-Pinto, Ana ;
Sole, Brisa ;
Reinares, Maria ;
Gonzalez-Ortega, Itxaso ;
Alberich, Susana ;
Manuel Crespo, Jose ;
Salamero, Manel ;
Vieta, Eduard ;
Martinez-Aran, Anabel ;
Torrent, Carla .
JOURNAL OF AFFECTIVE DISORDERS, 2014, 160 :50-54